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Publications

Publications by year: |2024| |2023| |2022| |2021|2020 |2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | Before UW-Madison

   

2024

404 Huang W, Son MH, Ha LN, Kang L, Cai W. Challenges coexist with opportunities: development of a macrocyclic peptide PET radioligand for PD‑L1. European Journal of Nuclear Medicine and Molecular Imaging, 2024, 51, 1574-1577. (PMCID: pending)
403 Zhao Y, Hsu JC, Hu S, Cai W. PET imaging of PD-L1 with a small molecule radiotracer. European Journal of Nuclear Medicine and Molecular Imaging, 2024, 51, 1578-1581. (PMCID: PMC11042986)
402 Huang W, Son MH, Ha LN, Kang L, Cai W. More than meets the eye: 2‑[18F]FDG PET‑based radiomics predicts lymph node metastasis in colorectal cancer patients to enable precision medicine. European Journal of Nuclear Medicine and Molecular Imaging, 2024, 51, 1725-1728. (PMCID: PMC11042987)
401 Zhang Y, Cao M, Wu Y, Malih S, Xu D, Yang E, Younis MH, Lin W, Zhao H, Wang C, Liu Q, Engle JW, Rasaee MJ, Guan Y, Huang G, Liu J, Cai W, Xie F, Wei W. Preclinical development of novel PD-L1 tracers and first-in-human study of [68Ga]Ga-NOTA-RW102 in patients with lung cancers. Journal for ImmunoTherapy of Cancer, 2024, 12, e008794. (PMCID: PMC11002357)
400 Tang Z, Yu F, Hsu JC, Shi J, Cai W. Soybean oil-derived lipids for efficient mRNA delivery. Advanced Materials, 2024, 36, e2302901. (PMCID: PMC10996393)
399 Ghosh S, Patra S, Younis MH, Chakraborty A, Guleria A, Gupta SK, Singh K, Rakhshit S, Chakraborty S, Cai W, Chakravarty R. 2024 Brachytherapy at the nanoscale with protein functionalized and intrinsically radiolabeled [169Yb]Yb2O3 nanoseeds. European Journal of Nuclear Medicine and Molecular Imaging, 2024, 51, 1558-1573. (PMCID: PMC11042995)
398 Malih S, Lin W, Tang Z, DeLuca MC, Engle JW, Alirezapour B, Cai W, Rasaee MJ. Noninvasive PET imaging of tumor PD-L1 expression with 64Cu-labeled durvalumab. American Journal of Nuclear Medicine and Molecular Imaging, 2024, 14, 31-40. (PMCID: PMC10944374)
397 Hu Q, Zuo H, Hsu JC, Zeng C, Tian Z, Sun Z, Cai W, Tang Z, Chen W. The emerging landscape for combating resistance associated with energy-based therapies via nanomedicine. Advanced Materials, 2024, 36, e2308286024. (PMCID: PMC10872442)
396 Ghosh S, Lee SJ, Hsu JC, Chakraborty S, Chakravarty R, Cai W. Cancer brachytherapy at the nanoscale: An emerging paradigm. Chemical & Biomedical Imaging, 2024, 2, 4-26. (PMCID: PMC10806911)
   

2023

395 Ji X, Zhu L, Hsu JC, Wang H, Zhou J, Wang Q, Li Y, Cai W, Ni D, Wu Z. Tungsten-based nanoparticles as contrast agents for liver tumor detection using dual-energy computed tomography. Biomaterials Science, 2023, 11, 7817-7825. (PMCID: PMC10873050)
394 Pedraza ZS, Wang Y, Carlos C, Tang Z, Li J, Cai W, Wang X. Development of ferroelectric P(VDF-TrFE) microparticles for ultrasound-driven cancer cell killing. ACS Applied Materials & Interfaces, 2023, 15, 54304-54311. (PMCID: PMC10867862)
393 Huang W, Tao Z, Younis MH, Cai W, Kang L. Nuclear medicine radiomics in digestive system tumors: Concept, applications, challenges, and future perspectives. VIEW, 2023, 4, 20230032. (PMCID: PMC10766416)
392 Yan J, Tang Z, Li Y, Wang H, Hsu JC, Shi M, Fu Z, Ji X, Cai W, Ni D, Qu J. Molybdenum nanodots for acute lung injury therapy. ACS Nano, 2023, 17, 23872-23888. (PMCID: PMC10760930)
391 Yang Q, Huang W, Hsu JC, Song L, Sun X, Li C, Cai W, Kang L. CD146-targeted nuclear medicine imaging in cancer: State of the art. VIEW, 2023, 4, 20220085. (PMCID: PMC10703309)
390 Hsu JS, Tang Z, Eremina OE, Sofias AM, Lammers T, Lovell JF, Zavaleta C, Cai W, Cormode DP. Nanomaterial-based contrast agents. Nature Reviews Methods Primers, 2023, 3, 30.(PMCID: PMC10732545)
389 Jiang D, Lan X, Cai W. PET imaging of nectin-4: A promising tool for personalized/precision oncology. Clinical Cancer Research, 2023, 29, 3259-3261. (PMCID: PMC10529329)
388 Rosenkrans ZT, Hsu JC, Aluicio-Sarduy E, Barnhart TE, Engle JW, Cai W. Amplification of Cerenkov luminescence using semiconducting polymers for cancer theranostics. Advanced Functional Materials, 2023, 33, 2302777. (PMCID: PMC10629852)
387 Chakravarty R, Song W, Chakraborty S, Cai W. Fibroblast activation protein (FAP)-targeted radionuclide therapy: Which ligand is the best? European Journal of Nuclear Medicine and Molecular Imaging, 2023, 50, 2935-2939. (PMCID: PMC10428190)
386 Li X, Lan X, Cai W. Pretargeted radioimmunotherapy of ovarian cancer with 225Ac and an internalizing antibody. Journal of Nuclear Medicine, 2023, 64, 1446-1448. (PMCID: PMC10478819)
385 Song W, Wei W, Lan X, Cai W. Albumin binding improves nanobody pharmacokinetics for dual‑modality PET/NIRF imaging of CEACAM5 in colorectal cancer models. European Journal of Nuclear Medicine and Molecular Imaging, 2023, 50, 2591-2594. (PMCID: 10330897)
384 Xu Y, Hsu JC, Xu L, Chen W, Cai W, Wang K. Nanomedicine-based adjuvant therapy: a promising solution for lung cancer. Journal of Nanobiotechnology, 2023, 21, 211. (PMCID: PMC10327390)
383 Zhu T, Hsu JC, Guo J, Chen W, Cai W, Wang K. Radionuclide‑based theranostics — a promising strategy for lung cancer. European Journal of Nuclear Medicine and Molecular Imaging, 2023, 50, 2353-2374. (PMCID: PMC10272099)
382 Forgham H, Lui L, Zhu J, Javed I, Cai W, Qiao R, Davis TP. Vector enabled CRISPR gene editing – A revolutionary strategy for targeting the diversity of brain pathologies. Coordination Chemistry Reviews, 2023, 487, 215172. (PMCID: PMC10249757)
381 Song W, Hsu JC, Lan X, Cai W. Optical image‑guided therapy of pancreatic cancer with an ultra‑small bispecific protein. European Journal of Nuclear Medicine and Molecular Imaging, 2023, 50, 1560-1563. (PMCID: PMC10121951)
380 Chakravarty R, Lan X, Chakraborty S, Cai W. Astatine‑211 for PSMA‑targeted α‑radiation therapy of micrometastatic prostate cancer: a sustainable approach towards precision oncology. European Journal of Nuclear Medicine and Molecular Imaging, 2023, 50, 1844-1847. (PMCID: PMC10200747)
379 Sperger JM, Helzer KT, Stahlfeld CN, Jiang D, Singh A, Kaufmann KR, Niles DJ, Heninger E, Rydzewski NR, Wang K, Wang L, Yang R, Ren Y, Engle JW, Huang P, Kyriakopoulos CE, Slovin SF, Soule HR, Zhao SG, Kohli M, Tagawa ST, Cai W, Dehm SM, Lang JM. Expression and therapeutic targeting of TROP-2 in treatment-resistant prostate cancer. Clinical Cancer Research, 2023, 29, 2324-2335. (PMCID: PMC10261916)
378 Li X, Younis MH, Wei W, Cai W. PD‑L1−targeted magnetic fluorescent hybrid nanoparticles: Illuminating the path of image‑guided cancer immunotherapy. European Journal of Nuclear Medicine and Molecular Imaging, 2023, 50, 2240–2243.(PMCID: PMC10272096)
377 Du Y, Huo Y, Yang Q, Han Z, Hou L, Cui B, Fan K, Qiu Y, Chen Z, Huang W, Lu J, Cheng L, Cai W, Kang L. Ultrasmall iron-gallic acid coordination polymer nanodots with antioxidative neuroprotection for PET/MR imaging-guided ischemia stroke therapy. Exploration, 2023, 3, 20220041. (PMCID: PMC10190924)
376 Kostka L, Kotrchová L, Randárová E, Ferreira CA, Malátová I, Lee HJ, Olson AP, Engle JW, Kovář M, Cai W, Šírová M, Etrych T. Evaluation of linear versus star-like polymer anti-cancer nanomedicines in mouse models. Journal of Controlled Release, 2023, 353, 549-562. (PMCID: PMC9892306)
375 Wu S, Fan K, Yang Q, Chen Z, Hou Y, Zou Y, Cai W, Kang L. Smart nanoparticles and microbeads for interventional embolization therapy of liver cancer: state of the art. Journal of Nanobiotechnology, 2023, 21, 42. (PMCID: PMC9901004)
374 Li X, Hsu JC, Son MH, Ha LN, Cai W. Cancer photodynamic therapy with chlorin e6-loaded, goat milk-derived extracellular vesicles: [18F]FDG lights up the way. European Journal of Nuclear Medicine and Molecular Imaging, 2023, 50, 247-25. (PMCID: PMC9822859)
373 Wei H, Jiang D, Yu B, Ni D, Li M, Long Y, Ellison PA, Siamof CM, Cheng L, Barnhart TE, Im H-J, Yu F, Lan X, Zhu X, He Q, Cai W. Nanostructured polyvinylpyrrolidone-curcumin conjugates allowed for kidney-targeted treatment of cisplatin induced acute kidney injury. Bioactive Material, 2023, 19, 282-291. (PMCID: PMC9058893)
372 Song W, Zhang X, Song Y, Shao F, Fan K, Shao F, Long Y, Gao Y, Cai W, Lan X. Enhancing photothermal therapy efficacy by in situ self-assembly in glioma. ACS Applied Materials & Interfaces, 2023, 15, 57-66. (PMCID: PMC9839507)
   

2022

371 Wang Y, Zhang H,Liu Y,Younis MH, Cai W, Bu W. Catalytic radiosensitization: Insights from materials physicochemistry. Materials Today, 2022, 57, 262-278. (PMCID: PMC9681018)
370 Wang Y, Zhang L, Liu Y, Tang L, Sun X, Younis MH, Cui D, Xiao H, Gao D, Kong X-Y, Cai W, Song J. Engineering CpG-ASO-Pt-loaded macrophages (CAP@M) for synergistic chemo-/gene-/immuno-therapy. Advanced Healthcare Materials, 2022, 11, 2201178. (PMCID: PMC9664705)
369 Wang Y, Chen-Mayfield T-J, Li Z, Younis MH, Cai W, Hu Q. Harnessing DNA for immunotherapy: Cancer, infectious diseases, and beyond. Advanced Functional Materials, 2022, 32, 2112273. (PMCID: PMC9595111)
368 Wei W, Younis MH, Lan X, Liu J, Cai W. Single-domain antibody theranostics on the horizon. Journal of Nuclear Medicine, 2022, 63, 1475-1479. (PMCID: PMC9536702)
367 Li Y, Younis MH, Wang H, Zhang J, Cai W, Ni D. Spectral computed tomography with inorganic nanomaterials: State-of-the-art. Advanced Drug Delivery Reviews, 2022, 189, 114524. (PMCID: PMC9664656)
366 Tang Z, Wu S, Zhao P, Wang H, Ni D, Li H, Jiang X, Wu Y, Meng Y, Yao Z, Cai W, Bu W. Chemical factory-guaranteed enhanced chemodynamic therapy for orthotopic liver cancer. Advanced Science, 2022, 9, 2201232. (PMCID: PMC9376848)
365 Younis MH, Tang Z, Cai W. Multimodality imaging of nanoparticle-based vaccines: shedding light on immunology. WIREs Nanomedicine & Nanobiotechnolog, 2022, 14, e1807. (PMCID: PMC9481661)
364 Li S, Wang Y, Wu M, Younis MH, Olson AP, Barnhart TE, Engle JW, Zhu X, Cai W. Spleen-targeted glabridin-loaded nanoparticles regulate polarization of monocyte/macrophage (Mo/Mϕ) for the treatment of cerebral ischemia-reperfusion injury. Advanced Materials, 2022, 34, 2204976. (PMCID: PMC9594991)
363 Lu Q, Long Y, Fan K, Shen Z, Gai Y, Liu Q, Jiang D, Cai W, Wan C, Lan X. PET imaging of hepatocellular carcinoma by targeting tumor‑associated endothelium using [68Ga]Ga‑PSMA‑617. European Journal of Nuclear Medicine and Molecular Imaging,, 2022, 49, 4000-4013. (PMCID: PMC9529836)
362 Zhu X, Xue C, Kang X, Jia X, Wang L, Younis MH, Liu D, Huo N, Han Y, Chen Z, Fu J, Zhou C, Yao X, Du Y, Cai W, Kang L, Lyu Z. DNMT3B-mediated FAM111B methylation promotes papillary thyroid tumor glycolysis, growth and metastasis. International Journal of Biological Sciences, 2022, 49, 2844-2868. (PMCID: PMC9295055)
361 Li M, Younis MH, Zhang Y, Cai W, Lan X. Clinical summary of fibroblast activation protein inhibitor-based radiopharmaceuticals: Cancer and beyond. European Journal of Nuclear Medicine and Molecular Imaging, 2022, 18, 4372-4387. (PMCID: PMC9232873)
360 Lan X, Huo L, Li S, Wang J, Cai W. State-of-the-art of nuclear medicine and molecular imaging in China: after the first 66 years (1956-2022) European Journal of Nuclear Medicine and Molecular Imaging, 2022, 49, 2455-2461. (PMCID: PMC9167647)
359 Chen W, Younis MH, Zhao Z, Cai W. Recent biomedical advances enabled by HaloTag technology BIOCELL, 2022, 46, 1789-1801. (PMCID: PMC9119580)
358 Younis MH, Lan X, Cai W. PET with a 68Ga-labeled FAPI dimer: moving toward theranostics. Journal of Nuclear Medicine, 2022, 63, 860-861. (PMCID: PMC9157727)
357 Younis MH, Malih S, Lan X, Rasaee MJ, Cai W. Enhancing fibroblast activation protein (FAP)-targeted radionuclide therapy with albumin binding, and beyond. European Journal of Nuclear Medicine and Molecular Imaging, 2022, 49, 1773-1777. (PMCID: PMC9074086)
356 Kang L, Li C, Yang Q, Sutherlin L, Wang L, Chen Z, Becker KV, Huo N, Qiu Y, Engle JW, Wang R, He C, Jiang D, Xu X, Cai W. 64Cu-labeled daratumumab F(ab')2 fragment enables early visualization of CD38-positive lymphoma. European Journal of Nuclear Medicine and Molecular Imaging, 2022, 49, 1470-1481. (PMCID: PMC8940612)
355 Wang H, Guo J, Lin W, Fu Z, Ji X, Yu B, Lu M, Cui W, Deng L, Engle JW, Wu Z, Cai W, Ni D. Open-shell nanosensitizers for glutathione responsive cancer sonodynamic therapy. Advanced Materials, 2022, 34, 2110283. (PMCID: PMC9012683)
354 Song Y, Song W, Lan X, Cai W, Jiang D. Spherical nucleic acids: Organized nucleotide aggregates as versatile nanomedicine. Aggregate, 2022, 3, e120. (PMCID: PMC8982904)(Front Cover)
353 Chen W, Li M, Younis MH, Barnhart TE, Jiang D, Sun T, Lang JM, Engle JW, Zhou M, Cai W. ImmunoPET of trophoblast cell-surface antigen 2 (Trop-2) expression in pancreatic cancer. European Journal of Nuclear Medicine and Molecular Imaging, 2022, 49, 861-870. (PMCID: PMC8810666)
   

2021

352 Qin C, Song Y, Cai W, Lan X. Dimeric FAPI with potential for tumor theranostics. American Journal of Nuclear Medicine and Molecular Imaging, 2021, 11, 537-541. (PMCID: PMC8727879)
351 Li H, Liu Z, Yuan L, Fan K, Zhang Y, Cai W, Lan X. Radionuclide-based imaging of breast cancer: state-of-the-art. Cancers, 2021, 13, 5459. (PMCID: PMC8582396)
350 Yang F, Li J, Long Y, Zhang Z, Wang L, Sui J, Dong Y, Wang Y, Taylor R, Ni D, Cai W, Wang P, Hacker T, Wang X. Wafer-scale heterostructured piezoelectric bio-organic thin films. Science, 2021, 373, 337-342. (PMCID: PMC8516594)
349 Lan X, Fan K, Li K, Cai W. Dynamic PET imaging with ultra-low-activity of 18F-FDG: Unleashing the potential of total-body PET. European Journal of Nuclear Medicine and Molecular Imaging, 2021, 48, 4138-4141. (PMCID: PMC8322144)
348 Han S, Ma W, Jiang D, Sutherlin L, Zhang J, Lu Y, Huo N, Chen Z, Engle JW, Wang Y, Xu X, Kang L, Cai W, Wang L.Intracellular signaling pathway in dendritic cells and antigen transport pathway in vivo mediated by an OVA@DDAB/PLGA nano‑vaccine. Journal of Nanobiotechnology, 2021, 19, 394.(PMCID: PMC8626881)
347 Lan X, Younis MH, Li K, Cai W. First clinical experience of 106 cm, long axial field-of-view (LAFOV) PET/CT: an elegant balance between standard axial (23 cm) and total-body (194 cm) systems. European Journal of Nuclear Medicine and Molecular Imaging, 2021, 48, 3755-3759. (PMCID: PMC8381142)
346 Li J, Hacker TA, Wei H, Long Y, Yang F, Ni D, Rodgers A, Cai W, Wang X. Long-term in vivo operation of implanted cardiac nanogenerators in swine. Nano Energy, 2021, 90, 106507. (PMCID: PMC8562697)
345 Fang H, Younis MH, Cai W, Lan X, Jiang D. New wine in old bottles: 68Ga-PSMA-11 PET/CT reveals COVID-19 in patients with prostate cancer. American Journal of Nuclear Medicine and Molecular Imaging, 2021, 11, 332-336. (PMCID: PMC8414401)
344 Song Y, Liu F, Ruan W, Hu F, Younis MH, Gao Z, Ming J, Huang T, Cai W, Lan X. Head-to-head comparison of neck 18F-FDG PET/MR and PET/CT in the diagnosis of differentiated thyroid carcinoma patients after comprehensive treatment. Cancers, 2021, 13, 3436. (PMCID: PMC8307331)
343 Yao G, Kang L, Li C, Chen S, Wang Q, Yang J, Long Y, Li J, Zhao K, Xu W, Cai W, Lin Y, Wang X. A self-powered implantable and bioresorbable electrostimulation device for biofeedback bone fracture healing. Proceedings of the National Academy of Sciences of the United States of America, 2021, 118, e2100772118. (PMCID: PMC8414402)
342 Li K, Zhang R, Cai W. Deep learning convolutional neural network (DLCNN): Unleashing the potential of 18F-FDG PET/CT in lymphoma. American Journal of Nuclear Medicine and Molecular Imaging, 2021, 11, 327-331. (PMCID: PMC8414402)
341 First-in-human study of an 18F-labeled boramino acid: a new class of PET tracers. European Journal of Nuclear Medicine and Molecular Imaging, 2021, 11, 9214-9216. (PMCID: PMC8339148)
340 Jiang D, Younis MH, Lan X, Cai W. High-performance renal imaging with a radiolabeled, non-excretable chimeric fusion protein. Theranostics, 2021, 11, 9214-9216. (PMCID: PMC8419045)
339 Shi S, Goel S, Lan X, Cai W. ImmunoPET of CD38 with a radiolabeled nanobody: promising for clinical translation. European Journal of Nuclear Medicine and Molecular Imaging, 2021, 48, 2683-2686. (PMCID: PMC8266735)
338 Zhang X, Hu J, Becker KV, Engle JW, Ni D, Cai W, Wu D, Qu S. Antioxidant and C5a-blocking strategy for hepatic ischemia-reperfusion injury repair. Journal of Nanobiotechnology, 2021, 19, 107. (PMCID: PMC8050892)
337 Shan L, Zhang T, Fan K, Cai W, Liu H. Astrocyte-neuron signaling in synaptogenesis. Advanced Healthcare Materials, 2021, 9, 680301. (PMCID: PMC8284252)
336 Sier VQ, van der Vorst JR,Quax PHA,de Vries MR,Zonoobi E,Vahrmeijer AL, Dekkers IA,de Geus-Oei L-F,Smits AM, Cai W, Sier CFM,Goumans MJTH,Hawinkels LJAC. Endoglin/CD105-based imaging of cancer and cardiovascular diseases: A systematic review. International Journal of Molecular Sciences, 2021, 22, 4804. (PMCID: PMC8124553)
335 Li C, Kang L, Fan K, Ferreira CA, Becker KV, Huo N, Liu H, Yang Y, Engle JW, Wang R, Xu X, Jiang D, Cai W. ImmunoPET of CD146 in orthotopic and metastatic breast cancer models. Bioconjugate Chemistry, 2021, 32, 1306-1314. (PMCID: PMC8292437)
334 Ferreira CA, Kang L, Li C, Kamkaew A, Barrett KE, Aluicio-Sarduy E, Yang Y, Engle JW, Jiang D, Cai W.ImmunoPET of the differential expression of CD146 in breast cancer. American Journal of Cancer Research, 2021, 11, 1586-1599. (PMCID: PMC8085863)
333 Jin Y, Liu B, Younis MH, Huang G, Liu J, Cai W, Wei W. Next-generation molecular imaging of thyroid cancer. Cancers, 2021, 13, 3188. (PMCID: PMC8268517)
332 Lin Y, Li C, Liu A, Zhen X, Gao J, Wu W, Cai W, Jiang X. Responsive hyaluronic acid-gold cluster hybrid nanogel theranostic systems. Biomaterials Science, 2021, 9, 1363-1373. (PMCID: PMC7934158)
331 Kang L, Li C, Rosenkrans ZT, Engle JW, Wang R, Jiang D, Xu X, Cai W. Noninvasive evaluation of CD20 expression using 64Cu-labeled F(ab')2 fragments of obinutuzumab in lymphoma. Journal of Nuclear Medicine, 2021, 62, 372-378. (PMCID: PMC8049347)
330 Kang L, Li C, Rosenkrans ZT, Huo N, Chen Z, Ehleding EB, Huo Y, Ferreira CA, Barnhart TE, Engle JW, Wang R, Jiang D, Xu X, Cai W. CD38-targeted theranostics of lymphoma with 89Zr/177Lu-labeled daratumumab. Advanced Sciences, 2021, 8, 2001879. (PMCID: PMC8132161)
329 Ferreira CA, Goel S, Ehlerding EB, Rosenkrans ZT, Jiang D, Sun T, Aluicio-Sarduy E, Engle JW, Ni D, Cai W. Ultrasmall porous silica nanoparticles with enhanced pharmacokinetics for cancer theranostics. Nano Letters, 2021, 21, 4692-4699. (PMCID: PMC8265214)
328 Kumar S, Jiang D, Sun B, Seeley KV, Engle JW, Sia Z, He X, Neelamegham S, Cai W, Lovell JF. Labeling of erythrocytes by porphyrin-phospholipid. Advanced Healthcare Materials, 2021, 1, 2000013. (PMCID: PMC8240482)
327 Li M, Wei W, Barnhart TE, Jiang D, Cao T, Fan K, Engle JW, Liu J, Chen W, Cai W. ImmunoPET/NIRF/Cerenkov multimodality imaging of ICAM-1 in pancreatic ductal adenocarcinoma. European Journal of Nuclear Medicine and Molecular Imaging, 2021, 48, 2737-2748. (PMCID: PMC8266732)
326 Ling X, Jin Z, Jiang Q, Wang X, Wei B, Wang Z, Xu Y, Cao T, Engle JW, Cai W, Su C, He Q. Engineering biocompatible TeSex nano-alloys as a versatile theranostic nanoplatform. National Science Review, 2021, 8, nwaa156. (PMCID: PMC8274553 )
325 Rosenkrans ZT, Ferreira CA, Ni D, Cai W. Internally responsive nanomaterials for activatable multimodal imaging of cancer. Advanced Healthcare Materials, 2021, 10, 2000690. (PMCID: PMC7855763)
   

2020

324 Zhang Z, Ni D, Wang F, Yin X, Goel S, German LN, Wang Y, Li J, Cai W, Wang X. In vitro study of enhanced photodynamic cancer cell killing effect by nanometer-thick gold nanosheets. Nano Research, 2020, 13, 3217-3223. (PMCID: PMC8291290)
323 Wei W, Jiang D, Lee HJ, Engle JW, Akiba H, Liu J, Cai W. ImmunoPET imaging of TIM-3 in murine melanoma models. Advanced Therapeutics, 2020, 3, 2000018. (PMCID: PMC8057702)
322 Li J, Long Y, Yang F, Wei H, Zhang Z, Wang Y, Wang J, Li C, Carlos C, Dong Y, Wu Y, Cai W, Wang X. Multifunctional artificial artery from direct 3D printing with built-in ferroelectricity and tissue-matching modulus for real-time sensing and occlusion monitoring. Advanced Functional Materials, 2020, 30, 2002868. (PMCID: PMC7928534)
321 Wei W, Jiang D, Lee HJ, Li M, Kutyreff CJ, Engle JW, Liu J, Cai W. Development and characterization of CD54-targeted immunoPET imaging in solid tumors. European Journal of Nuclear Medicine and Molecular Imaging, 2020, 47, 2765-2775. (PMCID: PMC7554090)
320 Siamof CM, Goel S, Cai W. Moving beyond the pillars of cancer treatment: perspectives from nanotechnology. Frontiers in Chemistry, 2020, 8, 598100. (PMCID: PMC7683771)
319 Jiang D, Rosenkrans ZT, Ni D, Lin J, Huang P, Cai W. Nanomedicines for renal management: from imaging to treatment. Accounts of Chemical Research, 2020, 53, 1869-1880. (PMCID: PMC7494607)
318 Long Y, Wei H, Li J, Li M, Wang Y, Zhang Z, Cao T, Carlos C, German LG, Jiang D, Sun T, Engle JW, Lan X, Jiang Y, Cai W, Wang X. Prevention of hepatic ischemia-reperfusion injury by carbohydrate-derived nanoantioxidants. Nano Letters, 2020, 20, 6510-6519. (PMCID: PMC7484346)
317 Li M, Ehlerding EB, Jiang D, Barnhart TE, Chen W, Cao T, Engle JW, Cai W. In vivo characterization of PD-L1 expression in breast cancer by immuno-PET with 89Zr-labeled avelumab. American Journal of Translational Research, 2020, 12, 1862-1872. (PMCID: PMC7270013)
316 Li L, Jaraquemada-Peláez MG, Aluicio-Sarduy E, Wang X, Barnhart TE, Cai W, Radchenko V, Schaffer P, Engle JW, Orvig C. Coordination chemistry of [Y(pypa)]− and comparison immuno-PET imaging of [44Sc]Sc- and [86Y]Y-pypa-phenyl-TRC105. Dalton Transactions, 2020, 49, 5547-5562. (PMCID: PMC7222037)
315 Qiao R, Fu C, Li Y, Qi X, Ni D, Nandakumar A, Siddiqui G, Wang H, Zhang Z, Wu T, Zhong J, Tang S-Y, Pan S, Zhang C, Whittaker MR, Engle JW, Creek DJ, Caruso F, Ke PC, Cai W, Whittaker AK, Davis TP. Sulfoxide-containing polymer-coated nanoparticles demonstrate minimal protein fouling and improved blood circulation. Advanced Sciences, 2020, 7, 2000406. (PMCID: PMC7341081)
314 Ferreira CA, Ehlerding EB, Rosenkrans ZT, Jiang D, Sun T, Aluicio-Sarduy E, Engle JW, Ni D, Cai W. 86/90Y-labeled monoclonal antibody targeting tissue factor for pancreatic cancer theranostics. Molecular Pharmaceutics, 2020, 17, 1697-1705. (PMCID: PMC7265990)
313 Wei W, Liu Q, Jiang D, Zhao H, Kutyreff CJ, Engle JW, Liu J, Cai W. Tissue factor-targeted immunoPET imaging and radioimmunotherapy of anaplastic thyroid cancer. Advanced Sciences, 2020, 7, 1903595. (PMCID: PMC7341097)
312 Li X, Rosenkrans ZT, Wang J, Cai W. PET imaging of macrophages in cardiovascular diseases. American Journal of Translational Research, 2020, 12, 1491-1514. (PMCID: PMC7270023)
311 Li L, Jaraquemada-Peláez MG, Aluicio-Sarduy E, Wang X, Jiang D, Sakheie M, Kuo HT, Barnhart TE, Cai W, Radchenko V, Schaffer P, Lin K-S, Engle JW, Bénard F, Orvig C. [nat/44Sc(pypa)]-: Thermodynamic stability, radiolabeling, and biodistribution of a prostate-specific-membrane-antigen-targeting conjugate. Inorganic Chemistry, 2020, 59, 1985-1995. (PMCID: PMC7408314)
310 Qian X, Shen T, Zhang X, Wang C, Cai W, Cheng R, Jiang X. Biologically active Camellia oleifera protein nanoparticles for improving the tumor microenvironment and drug delivery. Biomaterials Science, 2020, 8, 3907-3915. (PMCID: PMC7398584)
309 Rosenkrans ZT, Sun T, Jiang D, Chen W, Barnhart TE, Zhang Z, Ferreira CA, Wang X, Engle JW, Huang P, Cai W. Selenium-doped carbon quantum dots act as broad-spectrum antioxidants for acute kidney injury management. Advanced Science, 2020, 7, 2000420. (PMCID: PMC7312409)
308 Wei W, Rosenkrans ZT, Liu J, Huang G, Luo Q-Y, Cai W, Lan M, Zhang W. Self-amplified photodynamic therapy t. ImmunoPET: Concept, design, and applications. Chemical Reviews, 2020, 120, 3787-3851. (PMCID: PMC7265988)
307 Liu Z, Cao T, Xue Y, Li M, Wu M, Engle JW, He Q, Cai W, Lan M, Zhang W. Self-amplified photodynamic therapy through the 1O2-mediated internalization of photosensitizers from a Ppa-bearing block copolymer. Angewandte Chemie International Edition, 2020, 59, 3711-3717. (PMCID: PMC7028480)
306 Kostka L, Kotrchová L, Šubr V, Libánská A, Ferreira CA, Malátová I, Lee HJ, Barnhart TE, Engle JW, Cai W, Šírová M, Etrych T. HPMA-based star polymer biomaterials with tuneable structure and biodegradability tailored for advanced drug delivery to solid tumours. Biomaterials, 2020, 235, 119728. (PMCID: PMC7123463)
305 Huang Y, Fu Y, Li M, Jiang D, Kutyreff CJ, Engle JW, Lan X, Cai W, Chen T. Chirality-driven transportation and oxidation prevention by chiral selenium nanoparticles. Angewandte Chemie International Edition, 2020, 59, 4406-4414. (PMCID: PMC7123465)
304 Rosenkrans ZT, Cai W. Total-body PET imaging for up to 30 days after injection of 89Zr-labeled antibodies. Journal of Nuclear Medicine, 2020, 61, 451-452. (PMCID: PMC7067521)
303 Li S, Wang Y, Jiang D, Ni D, Kutyreff CJ, Barnhart TE, Engle JW, Cai W. Spatiotemporal distribution of Agrin after intrathecal injection and its protective role in cerebral ischemia/reperfusion injury. Advanced Science,2020, 7, 1902600. (PMCID: PMC7029627)
   

2019

302 Yu B, Ni D, Rosenkrans ZT, Barnhart TE, Wei H, Ferreira CA, Lan X, Engle JW, He Q, Yu F, Cai W. A “missile-detonation” strategy to precisely supply and efficiently amplify cerenkov radiation energy for cancer theranostics. Advanced Materials, 2019, 31, 1904894. (PMCID: PMC6928399)
301 Sun T, Jiang D, Rosenkrans ZT, Ehlerding EB, Ni D, Qi C, Kutyreff CJ, Barnhart TE, Engle JW, Huang P, Cai W. A melanin-based natural antioxidant defense nanosystem for theranostic application in acute kidney injury. Advanced Functional Materials, 2019, 29, 1904833. (PMCID: PMC7017599)
300 Jiang D, Im H-J, Boleyn ME, England CG, Ni D, Kang L, Engle JW, Huang P, Lan X, Cai W. Efficient renal clearance of DNA tetrahedron nanoparticles enables quantitative evaluation of kidney function. Nano Research, 2019, 12, 637-642. (PMCID: PMC7017644)
299 Wei W, Jiang D, Rosenkrans ZT, Barnhart TE, Engle JW, Luo Q-Y, Cai W. HER2-targeted multimodal imaging of anaplastic thyroid Cancer. American Journal of Cancer Research, 2019, 9, 2413-2427. (PMCID: PMC6895447)
298 Li S, Jiang D, Ehlerding EB, Rosenkrans ZT, Engle JW, Wang Y, Liu H, Ni D, Cai W. Intrathecal administration of nanoclusters for protecting neurons against oxidative stress in cerebral ischemia/reperfusion injury. ACS Nano, 2019, 13, 13382-13389. (PMCID: PMC6881527)
297 Goel S, Ferreira CA, Dogra P, Yu B, Kutyreff CJ, Siamof CM, Engle JW, Barnhart TE, Cristini V, Wang Z, Cai W. Size-optimized ultrasmall porous silica nanoparticles depict vasculature-based differential targeting in triple negative breast cancer. Small, 2019, 15, 1903747. (PMCID: PMC6854296)
296 Chen W, Ni D, Rosenkrans ZT, Cao T, Cai W. Smart H2S-triggered/therapeutic system (SHTS)-based nanomedicine. Advanced Science, 2019, 6, 1901724. (PMCID: PMC6864508)
295 Li S, Jiang D, Rosenkrans ZT, Barnhart TE, Ehlerding EB, Ni D, Engle JW, Cai W. Aptamer-conjugated framework nucleic acids for the repair of cerebral ischemia-reperfusion injury. ACS Nano, 2019, 19, 7334-7341. (PMCID: PMC6876547)
294 Yao G, Jiang D, Li J, Kang L, Chen S, Long Y, Wang Y, Huang P, Lin Y, Cai W, Wang X. Self-activated electrical stimulation for effective hair regeneration via a wearable omnidirectional pulse generator. ACS Nano, 2019, 13, 12345-12356. (PMCID: PMC6881522)
293 Qian X, Ge L, Yuan K, Li C, Zhen X, Cai W, Cheng R, Jiang X. Targeting and microenvironment-improving of phenylboronic acid-decorated soy protein nanoparticles with different sizes to tumor. Theranostics, 2019, 9, 7417-7430.(PMCID: PMC6831295)
292 Moukheiber D, Chitgupi U, Carter KA, Luo D, Sun B, Goel S, Ferreira CA, Engle JW, Wang D, Geng J, Zhang Y, Xia J, Cai W, Lovell JF. Surfactant-stripped pheophytin micelles for multimodal tumor imaging and photodynamic therapy. ACS Applied Bio Materials, 2019, 2, 544-554.(PMCID: PMC6919654)
291 Li S, England CG, Ehlerding EB, Kutyreff CJ, Engle JW, Jiang D, Cai W. ImmunoPET imaging of CD38 expression in hepatocellular carcinoma using 64Cu-labeled daratumumab. American Journal of Translational Research, 2019, 11, 6007-6015.(PMCID: PMC6682714)
290 Lee HJ, Ehlerding EB, Jiang D, Barnhart TE, Cao T, Wei W, Ferreira CA, Huang P, Engle JW, Cai W. Dual-labeled pertuzumab for multimodality image-guided ovarian tumor resection. American Journal of Cancer Research, 2019, 9, 1454-1468.(PMCID: PMC6682714)
289 Jiang D, Ni D, Rosenkrans ZT, Huang P, Yan X, Cai W. Nanozyme: new horizons for responsive biomedical applications. Chemical Society Reviews, 2019, 48, 3683-3704.(PMCID: PMC6696937)
288 Ni D, Wei H, Chen W, Bao Q, Rosenkrans ZT, Barnhart TE, Ferreira CA, Wang Y, Yao H, Sun T, Jiang D, Li S, Cao T, Liu Z, Engle JW, Hu P, Lan X, Cai W. Ceria nanoparticles meet hepatic ischemia-reperfusion injury: the perfect imperfection. Advanced Materials, 2019, 31, 1902956.(PMCID: PMC6773480)
287 Wei W, Ehlerding EB, Lan X, Luo Q-Y, Cai W. Molecular imaging of β-cells: diabetes and beyond. Advanced Drug Delivery Reviews, 2019, 139, 16-31.(PMCID: PMC6686871)
286 Ferreira CA, Ni D, Rosenkrans ZT, Cai W. Radionuclide-activated nanomaterials and their biomedical applications. Angewandte Chemie International Edition, 2019, 58, 13232-13252.(PMCID: PMC6698437)
285 Li M, Jiang D, Barnhart TE, Cao T, Engle JW, Chen W, Cai W. Immuno-PET imaging of VEGFR-2 expression in prostate cancer with 89Zr-labeled ramucirumab. American Journal of Cancer Research, 2019, 9, 2037-2046.(PMCID: PMC6650468)
284 Aluicio-Sarduy E, Hernandez R, Olson AP, Barnhart TE, Cai W, Ellison PA, Engle JW. Production and in vivo PET/CT imaging of the theranostic pair 132/135La. Scientific Reports, 2019, 9, 10658.(PMCID: PMC6650468)
283 Wei W, Rosenkrans ZT, Luo Q-Y, Lan X, Cai W. Exploiting nanomaterial-mediated autophagy for cancer therapy. Small Methods, 2019, 3, 1800365.(PMCID: PMC6660170)
282 Wei W, Jiang D, Ehlerding EB, Barnhart TE, Yang Y, Engle JW, Luo Q-Y, Huang P, Cai W. CD146-targeted multimodal image-guided photoimmunotherapy of melanoma. Advanced Science, 2019, 6, 1801237.(PMCID: PMC6498137)
281 Ehlerding EB, Lee HJ, Barnhart TE, Jiang D, Kang L, McNeel DG, Engle JW, Cai W. Noninvasive imaging and quantification of radiotherapy-induced PD-L1 upregulation with 89Zr-Df-atezolizumab. Bioconjugate Chemistry, 2019, 16, 2028-2036.(PMCID: PMC6521689 )
280 Wissler HL, Ehlerding EB, Lyu Z, Zhao Y, Zhang S, Eshraghi A, Buuh ZY, McGuth JC, Guan Y, Engle JW, Bartlett SJ, Voelz VA, Cai W, Wang RE. Site-specific immune-PET tracer to image PD-L1. Molecular Pharmeceutics, 2019, 16, 2028-2036.(PMCID: PMC6521698 )
279 Ehlerding EB, Lan X, Cai W. Predicting PD-1/PD-L1 status in bladder cancer with 18F-FDG PET? Journal of Nuclear Medicine and Molecular Imaging, 2019, 46, 791-793.(PMCID: PMC6451660 )
278 Lee HJ, Ehlerding EB, Cai W. Antibody-based tracers for PET/SPECT imaging of chronic inflammatory diseases. ChemBioChem, 2019, 20, 422-436.(PMCID: PMC6377337 )
277 Ehlerding EB, Lee HJ, Jiang D, Ferreira CA, Zahm CD, Huang P, Engle JW, McNeel DG, Cai W. Antibody and fragment-based PET imaging of CTLA-4+ T-cells in humanized mouse models. American Journal of Cancer Research, 2019, 9, 53-63. (PMCID: PMC6356917 )
276 Miyake M, Furuya H, Onishi S, Hokutan K, Ana S, Chan O, Shi S, Fujimoto K, Goodison S, Cai W, Rosser CJ. Monoclonal antibody against CXCL1 (HL2401) as a novel agent in suppressing IL6 expression and tumoral growth. Theranostics, 2019, 9, 853-867. (PMCID: PMC6376461 )
275 Ni D, Ehlerding EB, Cai W. Multimodality imaging agents with PET as a fundamental pillar. Angewandte Chemie International Edition, 2019, 58, 2570-2579.(PMCID: PMC6314921 )
   

2018

274 Li J, Kang L, Long Y, Wei H, Yu Y, Wang Y, Ferreira CA, Yao G, Zhang Z, Carlos C, German L, Lan X, Cai W, Wang X. Implanted battery-free direct-current micro-power supply from in vivo breath energy harvesting. ACS Applied Materials and Interfaces, 2018, 10, 42030-42038. (PMCID: PMC6456428 )
273 Long Y, Wei H, Li J, Yao G, Yu B, Ni D, Gibson ALF, Lan X, Jiang Y, Cai W, Wang X. Effective wound healing enabled by discrete alternative electric fields from wearable nanogenerators. ACS Nano, 2018, 12, 12533-12540. (PMCID: PMC6307171 )
272 Ni D, Ferreira CA, Barnhart TE, Quach V, Yu B, Jiang D, Wei W, Liu H, Engle JW, Hu P, Cai W. Magnetic targeting of nanotheranostics enhances Cerenkov radiation-induced photodynamic therapy. Journal of the American Chemical Society, 2018, 140, 14971-14979. (PMCID: PMC6310174 )
271 Yao G, Kang L, Li J, Long Y, Wei H, Ferreira CA, Jeffery JJ, Lin Y, Cai W, Wang X. Effective weight control via an implanted self-powered vagus nerve stimulation device. Nature Communications, 2018, 9, 5349. (PMCID: PMC6297229 )
270 Ni D, Jiang D, Kutyreff CJ, Lai J, Yan Y, Barnhart TE, Yu B, Im H-J, Kang L, Cho SY, Liu Z, Huang P, Engle JW, Cai W. Molybdenum-based nanoclusters act as antioxidants and ameliorate acute kidney injury in mice. Nature Communicatoins, 2018, 9, 5421. (PMCID: PMC6303396 )
269 Jiang D, Ge Z, Im H-J, England CG, Ni D, Hou J, Zhang L, Kutyreff CJ, Yan Y, Liu Y, Cho SY, Engle JW, Shi J, Huang P, Fan C, Yan H, Cai W. DNA origami nanostructures can exhibit preferential renal uptake and alleviate acute kidney injury. Nature Biomedical Engineering, 2018, 2, 865-877. (PMCID: PMC6258029 )
268 Liu T, Shi C, Duan L, Zhang Z, Luo L, Goel S, Cai W, Chen T. A highly hemocompatible erythrocyte membrane-coated ultrasmall selenium nanosystem for simultaneous cancer radiosensitization and precise antiangiogenesis. Journal of Materials Chemistry B, 2018, 6, 4756-4764. (PMCID: PMC6234506 )
267 Ferreira CA, Ni D, Rosenkrans ZT, Cai W. Scavenging of reactive oxygen and nitrogen species with nanomaterials. Nano Research, 2018, 11, 4955-4984. (PMCID: PMC6233906 )
266 Shi S, Chen F, Goel S, Graves SA, Luo H, Theuer CP, Engle JW, Cai W. In vivo tumor-targeted dual-modality PET/optical Imaging with a yolk/shell-structured silica nanosystem. Nano-Micro Letters , 2018, 10, 65. (PMCID: PMC6199109 )
265 Chen F, Goel S, Shi S, Barnhart TE, Lan X, Cai W. General Synthesis of Silica-based Yolk/shell Hybrid Nanomaterials and In Vivo Tumor Vasculature Targeting. Nano Research, 2018, 11, 4890-4904.(PMCID: PMC6217832 )
264 Wang D, Shi R, Zhou J, Shi S, Wu H, Xu P, Wang H, Xia G, Barnhart TE, Cai W,, Guo Z, Chen Q. Photo-enhanced singlet oxygen generation of prussian blue-based nanocatalyst for augmented photodynamic therapy. iScience, 2018, 9, 14-26.(PMCID: PMC6203243 )
263 Wei W, Ni D, Ehlerding EB, Luo Q, Cai W. PET imaging of receptor tyrosine kinases in cancer. Molecular Cancer Therapeutics, 2018, 17, 1625-1636.(PMCID: PMC6168319 )
262 Chakravarty R, Siamof CM, Dash A, Cai W. Targeted α-therapy of prostate cancer using radiolabeled PSMA inhibitors: A game changer in nuclear medicine. American Journal of Nuclear Medicine and Molecular Imaging, 2018, 8, 247-267.(PMCID: PMC6146164 )
261 Shi S, Chen F, Goel S, Graves SA, Luo H, Theuer CP, Engle JW, Cai W. In Vivo Tumor-Targeted Dual-Modality PET/Optical Imaging with a Yolk/Shell Structured Silica Nanosystem. Nano-Micro Letters, 2018, 51, 728-735.( PMCID: PMC6135531 )
260 Ferreira CA, Hernandez R, Yang Y, Valdovinos HF, Engle JW, Cai W. ImmunoPET of CD146 in a Murine Hindlimb Ischemia Model. Molecular Pharmaceutics, 2018,15,3434-3441.( PMCID:PMC6078808 )
259 Aluicio-Sarduy E, Ellison PA, Barnhart TE, Cai W, Nickles RJ, Engle JW. PET radiometals for antibody labeling. Journal of Labelled Compounds and Radiopharmaceuticals, 2018, 61, 636-651.( PMCID: PMC6050152 )
258 Ehlerding EB, Ferreira CA, Aluicio-Sarduy E, Jiang D, Lee HJ, Theuer CP, Engle JW, Cai W. 86/90Y-based theranostics targeting angiogenesis in a murine breast cancer model. Molecular Pharmaceutics, 2018, 15, 2606-2613.( PMCID: PMC6028311 )
257 Wei W, Jiang D, Ehlerding EB, Luo Q, Cai W. Noninvasive PET imaging of T cells. Trends in Cancer, 2018, 4, 359-373.( PMCID: PMC6034116 )
256 Zhan Y, Ehlerding EB, Shi S, Graves SA, Goel S, Engle JW, Liang J, Cai W. Intrinsically Zirconium-89-Labeled Manganese Oxide Nanoparticles for In Vivo Dual-Modality Positron Emission Tomography and Magnetic Resonance Imaging. Journal of Biomedical Nanotechnology, 2018, 14, 900-909.(PMCID: PMC6007016)
255 Kang L, Jiang D, England CG, Barnhart TE, Yu B, Rosenkrans ZT, Wang R, Engle JW, Xu X, Huang P, Cai W. ImmunoPET imaging of CD38 in murine lymphoma models using 89Zr-labeled daratumumab. European Journal of Nuclear Medicine and Molecular Imaging, 2018, 45, 1372-1381.(PMCID: PMC5994170)
254 Ni D, Jiang D, Ehlerding EB, Huang P, Cai W. Radiolabeling silica-based nanoparticles via coordination chemistry: basic principles, strategies, and applications. Accounts of Chemical Research, 2018, 51, 778-788.(PMCID: PMC5878690)
253 Lyu Z, Kang L, Buuh ZY, Jiang D, McGuth JC, Du J, Wissler HL, Cai W, Wang RE. A switchable site-specific antibody conjugate. ACS Chemical Biology, 2018, 15, 13, 958-964.(PMCID: PMC5910183)
252 Ehlerding EB, Cai W, Grodzinski P, Liu C. Big potential from small agents: nanoparticles for imaging-based companion diagnostics. ACS Nano, 2018, 12, 2106-2121.(PMCID: PMC5878691)
251 Xu C, Chen F, Valdovinos HF, Jiang D, Goel S, Yu B, Sun H, Barnhart TE, Moon JJ, Cai W. Bacteria-like mesoporous silica-coated gold nanorods for positron emission tomography and photoacoustic imaging-guided chemo-photothermal combined therapy. Biomaterials, 2018, 165, 56-65.(PMCID: PMC5880312)
250 Liu B, Jones M, Kong L, Noel T, Jeng EK, Shi S, England CG, Alter S, Miller JS, Cai W, Rhode PR, Wong HC. Evaluation of the biological activities of the IL-15 superagonist complex, ALT-803, following intravenous versus subcutaneous administration in murine models. Cytokine, 2018, 107, 105-112.(PMCID: PMC5916319)
249 Kang L, Jiang D, Ehlerding EB, Barnhart TE, Ni D, Engle JW, Wang R, Huang P, Xu X, Cai W. Noninvasive trafficking of brentuximab vedotin and PET imaging of CD30 in lung cancer murine models. Molecular Pharmaceutics, 2018, 15, 1627-1634.(PMCID: PMC5920523)
248 Yu B, Goel S, Ni D, Ellison PA, Jiang D, Kang L, Cheng L, Liu Z, Yu F, Barnhart TE, Huang P, He Q, Cai W. Positron Emission Tomography Imaging of Cell Membranes Cross-Linked Nano Micelles Excreted via a Hepatobiliary Route. Advanced Materials, 2018, 30, 1704934.(PMCID: PMC5878718)
247 Goel S, Ferreira CA, Chen F, Ellison PA, Siamof CM, Barnhart TE, Cai W. Activatable hybrid nanotheranostics for tetramodal imaging and synergistic photothermal/photodynamic therapy. Advanced Materials, 2018, 30, 1704367. (PMCID: PMC5805572)
246 Jadvar H, Chen X, Cai W, Mahmood U. Radiotheranostics in cancer management. Radiology, 2018, 286, 388-400. (PMCID: PMC5790308)
245 Ehlerding EB, Sun L, Lan X, Zeng D, Cai W. Dual-targeted molecular imaging of cancer. Journal of Nuclear Medicine, 2018, 59, 390-395. (PMCID: PMC5868496)
244 Liu Z, Ehlerding EB, Cai W, Lan X. One-step synthesis of an 18F-labeled boron-derived methionine analogue – a substitute for 11C-methionine? European Journal of Nuclear Medicine and Molecular Imaging, 2018, 45, 582-584. (PMCID: PMC5831531)
243 Ni D, Jiang D, Im H-J, Valdovinos HF, Yu B, Goel S, Barnhart TE, Huang P, Cai W. Radiolabeled polyoxometalate clusters: kidney dysfunction evaluation and tumor diagnosis by positron emission tomography imaging. Biomaterials, 2018, 171, 144-152. (PMCID: PMC5962344)
242 Ehlerding EB, Lan X, Cai W. “Albumin hitchhiking” with an Evans blue analog for cancer theranostics. Theranostics, 2018, 8, 812-814. (PMCID: PMC5771095)
241 Yu B, Wei H, He Q, Ferreira CA, Kutyreff CJ, Ni D, Rosenkrans ZT, Cheng L, Yu F, Engle JW, Lan X, Cai W. Efficient uptake of 177Lu-porphyrin-PEG nanocomplexes by tumor mitochondria for multimodal-imaging-guided combination therapy. Angewandte Chemie International Edition, 2018, 57, 218-222. (PMCID: PMC5745268)
240 Ehlerding EB, Lacognata S, Jiang D, Ferreira CA, Goel G, Hernandez R, Jeffery JJ, Theuer CP, Cai W. Targeting angiogenesis for radioimmunotherapy with a 177Lu-labeled antibody. European Journal of Nuclear Medicine and Molecular Imaging, 2018, 45, 123-131. (PMCID: PMC5700843)
239 Wei W, Ehlerding EB, Lan X, Luo Q, Cai W. PET and SEPCT imaging of melanoma: the state of the art. European Journal of Nuclear Medicine and Molecular Imaging, 2018, 45, 132-150. (PMCID: PMC5700861)
238 England CG, Jiang D, Ehlerding EB, Rekoske BT, Ellison PA, Hernandez R, Barnhart TE, McNeel DG, Huang P, Cai W. 89Zr-labeled nivolumab for imaging of T-cell infiltration in a humanized murine model of lung cancer. European Journal of Nuclear Medicine and Molecular Imaging, 2018, 45, 110-120. (PMCID: PMC5700850)
   

2017

237 Luo D, Goel S, Liu H-J, Carter KA, Jiang D, Geng J, Kutyreff CJ, Engle JW, Huang W-C, Shao S, Fang C, Cai W, Lovell JF. Intrabilayer 64Cu labeling of photoactivatable, doxorubicin-loaded stealth liposomes. ACS Nano, 2017, 11, 12482-12491. (PMCID: PMC6004286)
236 Cheng L, Shen S, Jiang D, Jin Q, Ellison PA, Ehlerding EB, Goel S, Song G, Huang P, Barnhart TE, Liu Z, Cai W. Chelator-free labeling of metal oxide nanostructures with zirconium-89 for positron emission tomography imaging. ACS Nano, 2017, 11, 12193-12201. (PMCID: PMC5752591)
235 Ni D, Bu W, Ehlerding EB, Cai W, Shi J. Engineering of inorganic nanoparticles as magnetic resonance imaging contrast agents. Chemical Society Reviews, 2017, 46, 7438-7468. (PMCID: PMC5705441)
234 Evangelista L, de Jong M, del Vecchio S, Cai W. The new era of cancer immunotherapy: What can molecular imaging do to help? Clinical and Translational Imaging, 2017, 5, 299-301. (PMCID: PMC5701751)
233 Valdovinos HF, Hernandez R, Graves S, Ellison PA, Barnhart TE, Theuer CP, Engle JW, Cai W, Nickles RJ. Cyclotron production and radiochemical separation of 55Co and 58mCo from 54Fe, 58Ni and 57Fe targets. Applied Radiation and Isotopes, 2017, 130, 90-101. (PMCID: PMC5673506)
232 Hernandez R, England CG, Yang Y, Valdovinos HF, Liu B, Wong HC, Barnhart TE, Cai W. ImmunoPET imaging of tissue factor expression in pancreatic cancer with 89Zr-Df-ALT-836. Journal of Controlled Release, 2017, 264, 160-168. (PMCID: PMC5632593)
231 Jin Q, Zhu W, Jiang D, Zhang R, Kutyreff CJ, Engle JW, Huang P, Cai W, Liu Z, Cheng L. Ultra-small iron-gallic acid coordination polymer nanoparticles for chelator-free labeling of 64Cu and multimodal imaging-guided photothermal therapy. Nanoscale, 2017, 9, 12609-12617. (PMCID: PMC5597939)
230 Shen S, Jiang D, Cheng L, Chao Y, Nie K, Dong Z, Kutyreff CJ, Engle JW, Huang P, Cai W, Liu Z. Renal-clearable ultrasmall coordination polymer nanodots for chelator-free 64Cu- labeling and imaging-guided enhanced radiotherapy of cancer. ACS Nano, 2017, 11, 9103-9111. (PMCID: PMC5617799)
229 Koziolová E, Goel S, Chytil P, Janoušková O, Barnhart TE, Cai W, Etrych T. A tumor-targeted polymer theranostics platform for positron emission tomography and fluorescence imaging. Nanoscale, 2017, 10906-10918. (PMCID: PMC5551419)
228 Cheng L, Jiang D, Kamkaew A, Valdovinos HF, Im H-J, Feng L, England CG, Goel S, Barnhart TE, Liu Z, Cai W. Renal-clearable PEGylated porphyrin nanoparticles for image-guided photodynamic cancer therapy. Advanced Functional Materials, 2017, 27, 1702928. (PMCID: PMC5687274)
227 Ehlerding EB, England CG, Jiang D, Graves SA, Kang L, Lacognata S, Barnhart TE, Cai W. CD38 as a PET imaging target in lung cancer. Molecular Pharmaceutics, 2017, 14, 2400-2406 (PMCID: PMC5552967)
226 England CG, Jiang D, Hernandez R, Sun H, Valdovinos HF, Ehlerding EB, Engle JW, Yang Y, Huang P, Cai W. ImmunoPET imaging of CD146 in murine models of intrapulmonary metastasis of non-small cell lung cancer. Molecular Pharmaceutics, 2017, 14, 3239-3247. (PMCID: PMC5624854)
225 Goel S, Ni D, Cai W. Harnessing the power of nanotechnology for enhanced radiation therapy. ACS Nano, 2017, 11, 5233-5237. (PMCID: PMC5552968)
224 Hernandez R, Graves SA, Gregg T, VanDeusen HR, Fenske RJ, Wienkes HN, England CG, Valdovinos HF, Jeffery JJ, Barnhart TE, Severin GW, Nickles RJ, Kimple ME, Merrins MJ, Cai W. Radiomanganese PET detects changes in functional β-cell mass in mouse models of diabetes. Diabetes, 2017, 66, 2163-2174. (PMCID: PMC5521871)
223 Ni D, Jiang D, Valdovinos HF, Ehlerding EB, Yu B, Barnhart TE, Huang P, Cai W. Bioresponsive polyoxometalate cluster for redox-activated photoacoustic imaging-guided photothermal cancer therapy. Nano Letters, 2017, 17, 3282-3289. (PMCID: PMC5495651)
222 Zhan Y, Shi S, Ehlerding EB, Graves SA, Goel S, Engle JW, Liang J, Tian J, Cai W. Radiolabeled, antibody-conjugated manganese oxide nanoparticles for tumor vasculature targeted positron emission tomography and magnetic resonance imaging. ACS Applied Materials & Interfaces, 2017, 9, 38304-38312. (PMCID: PMC5680099)
221 Ehlerding EB, England CG, Majewski RL, Valdovinos HF, Jiang D, Liu G, McNeel DG, Nickles RJ, Cai W. ImmunoPET imaging of CTLA-4 expression in mouse models of non-small cell lung cancer. Molecular Pharmaceutics, 2017, 14, 1782-1789. (PMCID: PMC5495656)
220 Jiang D, Im H-J, Sun H, Valdovinos HF, England CG, Ehlerding EB, Nickles RJ, Lee DS, Cho SY, Huang P, Cai W. Radiolabeled pertuzumab for imaging of human epidermal growth factor receptor 2 expression in ovarian cancer. European Journal of Nuclear Medicine and Molecular Imaging, 2017, 44, 1296-1305. (PMCID: PMC5471126)
219 Luo H, England CG, Goel S, Graves SA, Ai F, Liu B, Theuer CP, Wong HC, Nickles RJ, Cai W. ImmunoPET and near-infrared fluorescence imaging of pancreatic cancer with a dual-labeled bispecific antibody fragment. Molecular Pharmaceutics, 2017, 14, 1646-1655. (PMCID: PMC5473618)
218 Chakravarty R, Goel S, Dash A, Cai W. Radiolabeled inorganic nanoparticles for positron emission tomography imaging of cancer: an overview. Quarterly Journal of Nuclear Medicine and Molecular Imaging, 2017, 61, 181-204. (PMCID: PMC5477426)
217 Zhang Y, Hong H, Sun B, Carter K, Qin Y, Wei W, Wang D, Jeon M, Geng J, Nickles RJ, Chen G, Prasad PN, Kim C, Xia J, Cai W, Lovell JF. Surfactant-stripped naphthalocyanines for multimodal tumor theranostics with upconversion guidance cream. Nanoscale, 2017, 9, 3391-3398. (PMCID: PMC5435468)
216 Ellison PA, Chen F, Goel S, Barnhart TE, Nickles RJ, DeJesus OT, Cai W. Intrinsic and stable conjugation of thiolated mesoporous silica nanoparticles with radioarsenic. ACS Applied Materials & Interfaces, 2017, 9, 6772-678. (PMCID: PMC5597940)
215 Feng L, Cheng L, Dong Z, Tao D, Barnhart TE, Cai W, Chen M, Liu Z. Theranostic liposomes with hypoxia-activated prodrug to effectively destruct hypoxic tumors post-photodynamic therapy. ACS Nano, 2017, 11, 927-937. (PMCID: PMC5372701)
214 Kamkaew A, Fu N, Cai W, Burgess K. Novel small molecule probes for metastatic melanoma. ACS Medicinal Chemistry Letters, 2017, 8, 179-184 (PMCID: PMC5304293)
213 Heskamp S, Hernandez R, Molkenboer-Kuenen JDM, Essler M, Bruchertseifer F, Morgenstern A, Steenbergen EJ, Cai W, Seidl C, McBride WJ, Goldenberg DM, Boerman OC. α- versus β-emitting radionuclides for pretargeted radioimmunotherapy of carcinoembryonic antigen-expressing human colon cancer xenografts. Journal of Nuclear Medicine, 2017, 58, 926-933. (PMCID: PMC5450366)
212 Shi S, Xu C, Yang K, Goel S, Valdovinos HF, Luo H, Ehlerding EB, England CG, Cheng L, Chen F, Nickles RJ, Liu Z, Cai W. Chelator-free radiolabeling of nanographene: Breaking the stereotype of chelation. Angewandte Chemie International Edition, 2017, 56, 2889-2892. (PMCID: PMC5345346)
211 Chen F, Valdovinos HF, Hernandez R, Goel S, Barnhart TE, Cai W. Intrinsic radiolabeling of titanium-45 using mesoporous silica nanoparticles. Acta Pharmacologica Sinica, 2017, 38, 907-913. (PMCID: PMC5520186)
210 Graves SA, Hernandez R, Valdovinos HF, Ellison PA, Engle JW, Barnhart TE, Cai W, Nickles RJ. Preparation and in vivo characterization of 51MnCl2 as PET tracer of Ca2+ channel-mediated transport. Scientific Reports, 2017, 7, 3033. (PMCID: PMC5465055)
209 England CG, Rui L, Cai W. Lymphoma: Current status of clinical and preclinical imaging with radiolabeled antibodies. European Journal of Nulear Medicine and Molecular Imaging, 2017, 44, 517-532. (PMCID: PMC5285396)
208 Goel S, England CG, Chen F, Cai W. Positron emission tomography and nanotechnology: a dynamic duo for cancer theranostics. Advanced Drug Delivery Reviews, 2017, ePub. (PMCID: PMC5299094)
207 Hernandez R, Heskamp S, Rijpkema M, Bos DL, Goldenberg DM, McBride WJ, Morgenstern A, Bruchertseifer F, Cai W, Boerman OC. Preventing radiobleaching of cyanine fluorophores enhances stability of nuclear/NIRF multimodality imaging agents. Theranostics, 2017, 7, 1-8. (PMCID: PMC5196880)
206 England CG, Ehlerding EB, Hernandez R, Rekoske BT, Graves SA, Sun H, Liu G, McNeel DG, Barnhart TE, Cai W. Preclinical pharmacokinetics and biodistribution studies of 89Zr-labeled Pembrolizumab. Journal of Nuclear Medicine, 2017, 58, 162-168. (PMCID: PMC5209640)
   

2016

205 Yu Y, Sun H, Orbay H, Chen F, England CG, Cai W, Wang X. Biocompatibility and in vivo operation of implantable mesoporous PVDF-based nanogenerators. Nano Energy, 2016, 27, 275-281. (PMCID: pending)
204 Ai F, Goel S, Zhan Y, Valdovinos HF, Chen F, Barnhart TE, Cai W. Intrinsically 89Zr-labeled Gd2O2S:Eu nanophosphors with high in vivo stability for dual-modality imaging. American Journal of Translational Research, 2016, 8, 5591-5600. (PMCID: PMC5209509)
203 Zhang Y, Wang D, Goel S, Sun B, Chitgupi U, Geng J, Sun H, Barnhart TE, Cai W, Xia J, Lovell JF. Surfactant-stripped frozen pheophytin micelles for multimodal gut imaging. Advanced Materials, 2016, 28, 8524-8530. (PMCID: PMC5142297)
202 Brunnquell CL, Hernandez R, Graves SA, Smit-Oistad I, Nickles RJ, Cai W, Meyerand ME, Suzuki M. Uptake and retention of manganese contrast agents for PET and MRI in the rodent brain. Contrast Media & Molecular Imaging, 2016, 11, 371-380. (PMCID: PMC5140672)
201 Liu B, Kong L, Han K, Hong H, Marcus WD, Chen X, Jeng EK, Alter S, Zhu X, Rubinstein MP, Shi S, Rhode PR, Cai W, Wong HC. A novel fusion of ALT-803 (interleukin (IL)-15 superagonist) with an antibody demonstrates antigen-specific antitumor responses. Journal of Biological Chemistry, 2016, 291, 23869-23881.(PMCID: PMC5104912)
200 Kamkaew A, Cheng L, Goel S, Valdovinos HF, Barnhart TE, Liu Z, Cai W, Cerenkov radiation induced photodynamic therapy using chlorin e6-loaded hollow mesoporous silica nanoparticles. ACS Applied Materials & interfaces, 2016, 8, 26630-26637. (PMCID: PMC5061626)
199 Jiang D, England CG, Cai W, DNA nanomaterials for preclinical imaging and drug delivery. Journal of Controlled Release, 2016, 239, 27-38. (PMCID: PMC5037045)
198 Ehlerding EB, England CG, McNeel DG, Cai W, Molecular imaging of immunotherapy targets in cancer. Journal of Nuclear Medicine, 2016, 57, 1487-1492. (PMCID: PMC5050107)
197 Cheng L, Kamkaew A, Shen S, Valdovinos HF, Sun H, Hernandez R, Goel S, Liu T, Thompson CR, Barnhart TE, Liu Z, Cai W, Facile preparation of multifunctional WS2/WOx nanodots for chelator-free 89Zr-labeling and in vivo PET imaging. Small, 2016, 12, 5750-5758. (PMCID: PMC5093087)
196 Cheng L, Kamkaew A, Sun H, Jiang D, Valdovinos HF, Gong H, England CG, Goel S, Barnhart TE, Cai W, Dual-modality positron emission tomography/optical image-guided photodynamic cancer therapy with Chlorin e6-containing nanomicelles. ACS Nano, 2016, 10, 7721-7730. (PMCID: PMC4995128)
195 Hernandez R, Sun H, England CG, Valdovinos HF, Barnhart TE, Yang Y, Cai W. ImmunoPET imaging of CD146 expression in malignant brain tumors. Molecular Pharmaceutics, 2016, 13, 2563-2570. (PMCID: PMC4935599)
194 Hernandez R, Sun H, England CG, Valdovinos HF, Ehlerding EB, Barnhart TE, Yang Y, Cai W. CD146-targeted immunoPET and NIRF imaging of hepatocellular carcinoma with a dual-labeled monoclonal antibody. Theranostics, 2016, 6, 1918-1933. (PMCID: PMC4997246)
193 Im H-J, England CG, Feng L, Graves SA, Hernandez R, Nickles RJ, Liu Z, Lee DS, Cho SY, Cai W. Accelerated blood clearance phenomenon reduces the passive targeting of PEGylated nanoparticles in peripheral arterial disease. ACS Applied Materials & Interfaces, 2016, 6, 1918-1933.(PMCID: PMC4997246)
192 Sun H, England CG, Hernandez R, Graves SA, Majewski RL, Kamkaew A, Jiang D, Barnhart TE, Yang Y, Cai W. ImmunoPET for assessing the differential uptake of a CD146-specific monoclonal antibody in lung cancer. European Journal of Nuclear Medicine and Molecular Imaging, 2016, 8, 17955-17963. (PMCID: PMC4959540)
191 Lu W, Hong H, Cai W. Radio-nanomaterials for biomedical applications: state of the art. European Journal of Nanomedicine, 2016, , 8, 151-170. (PMCID: PMC4963156)
190 England CG, Ehlerding EB, Cai W. Imaging the biodistribution and performance of transplanted stem cells with PET. Journal of Nuclear Medicine, 2016,57, 1331-1332. (PMCID: PMC5010504)
189 Luo H, England CG, Shi S, Graves SA, Hernandez R, Yang Y, Liu B, Theuer CP, Wong HC, Nickles RJ, Cai W. Dual-targeting of tissue factor and CD105 for preclinical PET imaging of pancreatic cancer. Clinical Cancer Research, 2016, 22, 3821-3830. (PMCID: PMC4970931)
188 Xu C, Shi S, Feng L, Chen F, Graves SA, Goel S, Ehlerding EB, Sun H, England CG, Nickles RK, Liu Z, Wang T, Cai W. Long Circulating Reduced Graphene oxide/Fe3O4 Nanocomposite with Double PEGylation for Highly Efficient Tumor Targeting and Multimodal Imaging. Nanoscale, 2016, 8, 12683-12692. (PMCID: PMC4919229)
187 Ai F, Ferreira CA, Chen F, Cai W. Engineering of radiolabeled iron oxide nanoparticles for dual-modality imaging. Wiley Interdisciplinary Reviews (WIREs): Nanomedicine and Nanobiotechnology. 2016, 8, 619-630. (PMCID: PMC4911308)
186 Goel S, Chen F, Luan S, Valdovinos HF, Shi S, Graves SA, Ai F, Barnhart TE, Theuer CP, Cai W. Engineering intrinsically zirconium-89 radiolabeled self-destructing mesoporous silica nanostructures for in vivo biodistribution and tumor targeting studies. Advanced Science, 2016, 3, 1600122. (PMCID: PMC5102673)
185 England CG, Im H-J, Feng L, Chen F, Graves SA, Hernandez R, Orbay H, Xu C, Cho SY, Nickles RJ, Liu Z, Lee DS, Cai W. Re-assessing the enhanced permeability and retention effect in peripheral arterial disease using radiolabeled long circulating nanoparticles. Biomaterials, 2016, 100, 101-109. (PMCID: PMC4902717)
184 England CG, Kamkaew A, Im H-J, Valdovinos HF, Sun H, Hernandez R, Cho SY, Dunphy EJ, Lee DS, Barnhart TE, Cai W. ImmunoPET imaging of insulin-like growth factor 1 receptor in a subcutaneous mouse model of pancreatic cancer. Molecular Pharmaceutics, 2016, 13, 1958-1966. (PMCID: PMC4897730) (Selected as ACS Editors’ Choice for Immediate Open Access)
183 Ehlerding EB, Chen F, Cai W. Biodegradable and renal clearable inorganic nanoparticles. Advanced Science, 2016, 3, 1500223. (PMCID: PMC4944857)
182 Kamkaew A, Sun H, England CG, Cheng L, Liu Z, Cai W. Quantum dot – NanoLuc bioluminescence resonance energy transfer enables tumor imaging and lymph node mapping in vivo. Chemical Communications, 2016, 52, 6997-7000. (PMCID: PMC4912020)
181 Kamkaew A, Chen F, Zhan Y, Majewski RL, Cai W. Scintillating nanoparticles as energy mediators for enhanced photodynamic therapy. ACS Nano, 2016, 10, 3918-3935. (PMCID: PMC4846476)
180 England CG, Ehlerding EB, Cai W. NanoLuc: A small luciferase is brightening up the field of bioluminescence. Bioconjugate Chemistry, 2016, 27, 1175-1187. (PMCID: PMC4871753)
179 Chen F, Goel S, Hernandez R, Graves SA, Shi S, Nickles RJ, Cai W. Dynamic positron emission tomography imaging of renal clearable gold nanoparticles. Small, 2016, 12, 2775-2782. (PMCID: PMC4874869)
178 Zhan Y, Ai F, Chen F, Valdovinos HF, Orbay H, Sun H, Liang J, Barnhart TE, Tian J, Cai W. Intrinsically zirconium-89 labeled Gd2O2S:Eu nanoprobes for in vivo positron emission tomography and Gamma-ray-induced radioluminescence imaging. Small, 2016, 12, 2872-2876. (PMCID: PMC4889465)
177 Ehlerding EB, Cai W. Smaller agents for larger therapeutic indices: nanoscale brachytherapy with 177Lu-labeled gold nanoparticles. Journal of Nuclear Medicine, 2016, 57, 834-835. (PMCID: PMC4891258)
176 Ehlerding EB, Goel S, Cai W. Cancer theranostics with 64Cu/177Lu-loaded liposomes.  European Journal of Nuclear Medicine and Molecular Imaging, 2016, 43, 938-940. (PMCID: PMC4814333)
175 Cheng L, Shen S, Shi S, Yi Y, Wang X, Song G, Yang K, Liu G, Barnhart TE, Cai W, Liu Z. FeSe2-decorated Bi2Se3 nanosheets fabricated via cation exchange for chelator-free 64Cu-labeling and multimodal image-guided photothermal-radiation therapy. Advanced Functional Materials, 2016, 26, 2185-2197. (PMCID: PMC4838545)
174 Ellison PA, Barnhart TE, Chen F, Hong H, Zhang Y, Theuer CP, Cai W, Nickles RJ, DeJesus OT. High yield production and radiochemical isolation of isotopically pure arsenic-72 and novel radioarsenic labeling strategies for the development of theranostic radiopharmaceuticals. Bioconjugate Chemistry, 2016, 27, 179-188. (PMCID: PMC4720530)
173 England CG, Hernandez R, Eddine SBZ, Cai W. Molecular imaging of pancreatic cancer with antibodies. Molecular Pharmaceutics, 2016, 13, 8-24. (PMCID: PMC4701613)
172 Rhode PR, Egan JO, Xu W, Hong H, Webb GM, Chen X, Liu B, Zhu X, Wen J, You L, Kong L, Edwards AC, Han K, Shi S, Alter S, Sacha JB, Jeng EK, Cai W, Wong HC. Comparison of the superagonist complex, ALT-803, to IL15 as cancer immunotherapeutics in animal models. Cancer Immunology Research, 2016, 4, 49-60. (PMCID: PMC4703482)(Cover Feature)
171 Ehlerding EB, Cai W. Harnessing the power of molecular imaging for precision medicine. Journal of Nuclear Medicine, 2016, 57, 171-172. (PMCID: PMC4738016)
170 Luo H, England CG, Graves SA, Sun H, Liu G, Nickles RJ, Cai W. PET imaging of VEGFR-2 expression in lung cancer with 64Cu-labeled ramucirumab. Journal of Nuclear Medicine, 2016, 57, 285-290.(PMCID: PMC4738068)
169 Huang H, Hernandez R, Geng J, Sun H, Song W, Chen F, Graves SA, Nickles RJ, Cheng C, Cai W, Lovell JF. A porphyrin-PEG polymer with rapid renal clearance. Biomaterials, 2016, 76, 25-32. (PMCID: PMC4662896)

2015

168 Yang Y, Hernandez R, Rao J, Yin L, Qu Y, Wu J, England CG, Graves SA, Lewis CM, Wang P, Meyerand ME, Nickles RJ, Bian XW, Cai W. Targeting CD146 with a 64Cu-labeled antibody enables in vivo immunoPET imaging of high-grade gliomas. Proceedings of the National Academy of Sciences of the United States of America, 2015, 112, E6525-E6534. (PMCID: PMC4664343)
167 Luo H, Hernandez R, Hong H, Graves SA, Yang Y, England CG, Theuer CP, Nickles RJ, Cai W. Noninvasive brain cancer imaging with a bispecific antibody fragment, generated via click chemistry. Proceedings of the National Academy of Sciences of the United States of America. 2015, 112, 12806-12811. (PMCID: PMC4611632)
166 Shi S, Fliss BC, Gu Z, Zhu Y, Hong H, Valdovinos HF, Hernandez R, Goel S, Luo H, Chen F, Barnhart TE, Nickles RJ, Xu ZP, Cai W. Chelator-free labeling of layered double hydroxide nanoparticles for in vivo PET imaging. Scientific Reports, 2015, 5, 16930. (PMCID: PMC4653656)
165 Graves SA, Hernandez R, Fonslet J, England CG, Valdovinos HF, Ellison PA, Barnhart TE, Elema DR, Theuer CP, Cai W, Nickles RJ, Severin GW. Novel preparation methods of 52Mn for immunoPET imaging. Bioconjugate Chemistry, 2015, 26, 2118-2124. (PMCID: PMC4618027)
164 Chen F, Goel S, Valdovinos HF, Luo H, Hernandez R, Barnhart TE, Cai W. Chelator-free 89Zr-labeling of mesoporous silica nanoparticles with superb in vivo radio-stability. ACS Nano, 2015, 9, 7950-7959. (PMCID: PMC4550540)
163 Sun X, Cai W, Chen X. Positron emission tomography imaging using radiolabeled inorganic nanomaterials. Accounts of Chemical Research, 2015, 48, 286-294. (PMCID: PMC4540359)
162 Shi S, Orbay H, Yang Y, Graves SA, Nayak TR, Hong H, Hernandez R, Luo H, Goel S, Theuer CP, Nickles, RJ, Cai W. PET imaging of abdominal aortic aneurysm with a 64Cu-labeled antibody Fab fragment. Journal of Nuclear Medicine, 22015, 56, 927-932. (PMCID: PMC4452422)
161 Hernandez R, Czerwinski A, Chakravarty R, Yang Y, Graves SA, Nickles RJ, Cai W. Evaluation of two novel 64Cu-labelled RGD peptide derivatives for enhanced PET imaging of tumor integrin αvβ3. European Journal of Nuclear Medicine and Molecular Imaging, 2015, 42, 1859-1868. (PMCID: PMC4591102)
160 Shi S, Hong H, Orbay H, Graves SA, Yang Y, Ohman JD, Liu B, Nickles RJ, Wong HC, Cai W. ImmunoPET of tissue factor expression in triple-negative breast cancer with a radiolabeled antibody Fab fragment. European Journal of Nuclear Medicine and Molecular Imaging, 2015, 42, 1295-1303. (PMCID: PMC4482783)
159 Chakravarty R, Hong H, Cai W. Image-guided drug delivery with single-photon emission computed tomography: A review of literature. Current Drug Targets, 2015, 16, 592-609. (PMCID: PMC4346511)
158 England CG, Luo H, Cai W. HaloTag: a versatile platform for biomedical applications. Bioconjugate Chemistry, 2015, 26, 975-986. (PMCID: PMC4482335)
157 Dougherty CA, Cai W, Hong H. Applications of aptamers in targeted imaging: State of the art. Current Topics in Medicinal Chemistry, 2015, 15, 1138-1152. (PMCID: PMC4410081)
156 Chen F, Hong H, Goel S, Graves SA, Orbay H, Ehlerding EB, Shi S, Theuer CP, Nickles RJ, Cai W. In vivo tumor vasculature targeting of CuS@MSN based theranostic nanomedicine. ACS Nano, 2015, 9, 3926-3934. (PMCID: PMC4414921)
155 Liu T, Shi S, Liang C, Shen S, Cheng L, Wang C, Song X, Goel S, Barnhart TE, Cai W, Liu Z. Iron oxide decorated MoS2 nanosheets with double PEGylation for chelator-free radiolabeling and multimodal imaging guided photothermal therapy. ACS Nano, 2015, 9, 950-960. (PMCID: PMC4351725)
154 Hong H, Wang F, Zhang Y, Graves SA, Eddine SBZ, Yang Y, Theuer CP, Nickles RJ, Wang X, Cai W. Red fluorescent zinc oxide nanoparticle: A novel platform for cancer targeting. ACS Applied Materials & Interfaces, 2015, 7, 3373-3381. (PMCID:  PMC4326560)
153 Hong H, Yan Y, Shi S, Graves SA, Krasteva LK, Nickles RJ, Yang M, Cai W. PET of follicle-stimulating hormone receptor: broad applicability to cancer imaging. Molecular Pharmaceutics, 2015, 12, 403-410. (PMCID: PMC4351720)
152 Rieffel J, Chen F, Kim J, Chen G, Shao W, Shao S, Chitgupi U, Hernandez R, Graves SA, Nickles RJ, Prasad PN, Kim C, Cai W, Lovell JF. Hexamodal imaging with porphyrin-phospholipid-coated upconversion nanoparticles. Advanced Materials, 2015, 27, 1785-1790. (PMCID: PMC4416944)
151 Chen F, Cai W. Nanomedicine for targeted photothermal cancer therapy: where are we now? Nanomedicine, 2015, 10, 1-3. (PMCID: PMC4299941)
150 Luo H, Hong H, Slater MR, Graves SA, Shi S, Yang Y, Nickles RJ, Fan F, Cai W. PET of c-Met in cancer with 64Cu-labeled hepatocyte growth factor. Journal of Nuclear Medicine, 2015, 56, 758-763. (PMCID: PMC4417426)
149 Chakravarty R, Goel S, Hong H, Chen F, Valdovinos HF, Hernandez R, Barnhart TE, Cai W. Hollow mesoporous silica nanoparticles for tumor vasculature targeting and PET image-guided drug delivery. Nanomedicine, 2015, 10, 1233-1246. (PMCID: PMC4430331)
148 Valdovinos HF, Hernandez R, Barnhart TE, Graves S, Cai W, Nickles RJ. Separation of cyclotron-produced 44Sc from a natural calcium target using a dipentyl pentylphosphonate functionalized extraction resin. Applied Radiation and Isotopes, 2015, 95, 23-29. (PMCID: PMC4390433)
147 Lewis CM, Graves SA, Hernandez R, Valdovinos HF, Barnhart TE, Cai W, Meyerand ME, Nickles RJ, Suzuki M. 52Mn production for PET/MRI tracking of human stem cells expressing divalent metal transporter 1 (DMT1). Theranostics, 2015, 5, 227-239. (PMCID: PMC4279187)
146 Shi S, Yang K, Hong H, Chen F, Valdovinos HF, Goel S, Barnhart TE, Liu Z, Cai W. VEGFR targeting leads to significantly enhanced tumor uptake of nanographene oxide in vivo. Biomaterials, 2015, 39, 39-46. (PMCID: PMC4258896)

2014

145 Chen F, Ehlerding EB, Cai W. Theranostic Nanoparticles.Journal of Nuclear Medicine. 2014, 55, 1919-1922. (PMCID: PMC4255955)
144 Chakravarty R, Goel S, Valdovinos HF, Hernandez R, Hong H, Nickles RJ, Cai W. Matching the decay half-life with the biological half-life: ImmunoPET imaging with 44Sc-labeled cetuximab Fab fragment. Bioconjugate Chemistry, 2014, 25, 2197-2204. (PMCID: PMC4275156)
143  Shi S, Chen F, Ehlerding EB, Cai W. Surface engineering of graphene-based nanomaterials for biomedical applications.Bioconjugate Chemistry, 2014, 25, 1609-1619. (PMCID: PMC4166029)
142 Guo J,* Hong H,* Chen G, Shi S, Nayak TR, Theuer CP, Barnhart TE, Cai W, Gong S. Theranostic unimolecular micelles based on brush-shaped amphiphilic block copolymers for tumor-targeted drug delivery and positron emission tomography imaging. ACS Applied Materials & Interfaces, 2014, 6, 21769-21779. (PMCID: PMC4163544)
141
Zhang Y, Jeon M, Rich LJ, Hong H, Geng J, Zhang Y, Shi S, Barnhart TE, Alexandridis P, Huizinga JD, Seshadri M, Cai W, Kim C, Lovell JF. Non-invasive multimodal functional imaging of the intestine with frozen micellar naphthalocyanines. Nature Nanotechnology, 2014, 9, 631-638. (Highlighted in Science Translational Medicine, Chemical & Engineering News, Nature World News, Science World Report, Science Daily, and many other news media) (PMCID: PMC4130353)
140
Hong H,* Chen F,* Zhang Y, Cai W. New radiotracers for imaging of vascular targets in angiogenesis-related diseases. Advanced Drug Delivery Reviews, 2014, 76, 2-20. (PMCID: PMC4169744)
139
Hernandez R, Valdovinos HF, Yang Y, Chakravarty R, Hong H, Barnhart TE, Cai W. 44Sc: an attractive isotope for peptide-based PET imaging, Molecular Pharmaceutics, 2014, 11, 2954-2961. (PMCID: PMC4128785)
138
Hong H, Nayak TR, Shi S, Graves SA, Fliss BC, Barnhart TE, Cai W. Generation and screening of monoclonal antibodies for immunoPET imaging of IGF1R in prostate cancer. Molecular Pharmaceutics, 2014, 11, 3624-3630. (PMCID: PMC4186682)
137
Chakravarty R, Valdovinos HF, Chen F, Lewis CM, Ellison PA, Luo H, Meyerand ME, Nickles RJ, Cai W. Intrinsically germanium-69-labeled iron oxide nanoparticle: synthesis and in-vivo dual-modality PET/MR imaging. Advanced Materials, 2014, 26, 5119-5123. (PMCID: PMC4127144)
136 Chen F,* Hong H,* Shi S, Goel S, Valdovinos HF, Hernandez R, Theuer CP, Barnhart TE, Cai W. Engineering of hollow mesoporous silica nanoparticles for remarkably enhanced tumor active targeting efficacy. Scientific Reports, 2014, 4, 5080. (PMCID: PMC4038837)
135
Chen F, Nayak TR, Goel S, Valdovinos HF, Hong H, Theuer CP, Barnhart TE, Cai W. In vivo tumor vasculature targeted PET/NIRF imaging with TRC105(Fab)-conjugated, dual-labeled mesoporous silica nanoparticles. Molecular Pharmaceutics, 2014, 11, 4007−4014. (PMCID: PMC4218929)
134
Goel S, Chen F, Ehlerding EB, Cai W. Intrinsically radiolabeled nanoparticles: an emerging paradigm. Small, 2014, 10, 3825-3830. (Selected as Frontispiece) (PMCID: PMC4191998)
133 Chakravarty R, Hong H, Cai W. Positron emission tomography image-guided drug delivery: current status and future perspectives. Molecular Pharmaceutics, 2014, 11, 3777−3797. (PMCID: PMC4218872)
132
Luo H, Hong H, Yang SP, Cai W. Design and applications of bispecific heterodimers: molecular imaging and beyond.Molecular Pharmaceutics, 2014, 11, 1750-1761. (PMCID: PMC4051252
131  Goel S, Chen F, Hong H, Valdovinos HF, Hernandez R, Shi S, Barnhart TE, Cai W. VEGF121-conjugated mesoporous silica nanoparticle: a tumor targeted drug delivery system. ACS Applied Materials & Interfaces, 2014, 6, 21677-21685. (PMCID: PMC4262629)
130 Chen F, Cai W. Tumor vasculature targeting: a generally applicable approach for functionalized nanomaterials. Small, 2014, 10, 1887-1893. (PMCID: PMC4126500)
129
Wang L, Zhao Z, Meyer MB, Saha S, Yu M, Guo A, Wisinski KB, Huang W, Cai W, Pike JW, Yuan M, Ahlquist P, Xu W. CARM1 methylates chromatin remodeling factor BAF155 to enhance tumor progression and metastasis. Cancer Cell, 2014, 25, 21-36. (PMCID: PMC4004525)
128
Chakravarty R, Goel S, Cai W. Nanobody: The “magic bullet” for molecular imaging? Theranostics, 2014, 4, 386-398. (PMCID: PMC3936291)
127
Orbay H, Zhang Y, Valdovinos HF, Song G, Hernandez R, Theuer CP, Hacker TA, Nickles RJ, Cai W. Positron emission tomography imaging of CD105 expression in a rat myocardial infarction model with 64Cu-NOTA-TRC105. American Journal of Nuclear Medicine and Molecular Imaging, 2014, 4, 1-9. (PMCID: PMC3867724)
126
Orbay H, Hong H, Koch JM, Valdovinos HF, Hacker TA, Theuer CP, Barnhart TE, Cai W. Pravastatin stimulates angiogenesis in a murine hindlimb ischemia model: a positron emission tomography imaging study with 64Cu-NOTA-TRC105. American Journal of Translational Research, 2014, 6, 54-63. (PMCID: PMC3853424)
125
Goel S, Chen F, Cai W. Synthesis and biomedical applications of cupper sulfide nanoparticles: from sensors to theranostics. Small, 2014, 10, 631-645. (PMCID: PMC3960363)

 

2013

124
Orbay H, Bean J, Zhang Y, Cai W. Intraoperative targeted optical imaging: a guide towards tumor-free margins in cancer surgery. Current Pharmaceutical Biotechnology, 2013, 14, 733-742. (PMCID: PMC3946701)
123
Chen F,* Ellison PA,* Lewis CM, Hong H, Zhang Y, Shi S, Hernandez R, Meyerand ME, Barnhart TE, Cai W. Chelator-free synthesis of a dual-modality PET/MRI agent. Angewandte Chemie International Edition,2013, 52, 13319-13323. (Highly Important Paper) (PMCID: PMC3855680)
122
Chen F,* Hong H,* Zhang Y, Valdovinos HF, Shi S, Kwon GS, Theuer CP, Barnhart TE, Cai W. In vivo tumor targeting and image-guided drug delivery with antibody-conjugated, radiolabeled mesoporous silica nanoparticles. ACS Nano, 2013, 7, 9027-9039. (PMCID: PMC3834886)
121
Yang K, Feng L, Hong H, Cai W, Liu Z. Preparation and functionalization of graphene nanocomposites for biomedical applications. Nature Protocols, 2013, 8, 2392-2403. (PMCID: PMC3878091)
120
Chen F, Zhang Y, Cai W. Molecular MRI of VEGFR-2 reveals intra-tumor and inter-tumor heterogeneity. American Journal of Nuclear Medicine and Molecular Imaging, 2013, 3, 312-316. (PMCID: PMC3715775)
119
Shi S,* Chen F,* Cai W. Biomedical applications of functionalized hollow mesoporous silica nanoparticles: focusing on molecular imaging. Nanomedicine, 2013, 8, 2027-2039. (PMCID: PMC3844935)
118
Chen F, Bu W, Cai W, Shi J. Functionalized upconversion nanoparticles: versatile nanoplatforms for translational research. Current Molecular Medicine, 2013, 13, 1613-1632. (PMCID: PMC3845686)
117
Zhang Y, Nayak TR, Hong H, Cai W. Biomedical applications of zinc oxide nanomaterials. Current Molecular Medicine, 2013, 13, 1633-1645. (PMCID: PMC3838497)
116
Nayak TR, Hong H, Zhang Y, Cai W. Multimodality imaging of CXCR4 in cancer: current status towards clinical translation. Current Molecular Medicine, 2013, 13, 1538-1548. (PMCID: PMC3838476)
115
Wang RE, Zhang Y, Tian L, Cai W, Cai J. Antibody-based imaging of HER2: moving into the clinic. Current Molecular Medicine, 2013, 13, 1523-1537. (PMCID: PMC3852915)
114
Zhu Y, Hong H, Xu ZP, Li Z, Cai W. Quantum dot-based nanoprobes for in vivo targeted imaging. Current Molecular Medicine, 2013, 13, 1549-1567. (PMCID: PMC3838460)
113
Guo J,* Hong H,* Chen G, Shi S, Zheng Q, Zhang Y, Theuer CP, Barnhart TE, Cai W, Gong S. Image-guided and tumor-targeted drug delivery with radiolabeled unimolecular micelles. Biomaterials, 2013, 34, 8323-8332. (PMCID: PMC3785312)
112
Orbay H, Hong H, Zhang Y, Cai W. Positron emission tomography imaging of atherosclerosis. Theranostics, 2013, 3, 894-902. ( hrefPMCID: PMC3841339)
111
Orbay H,* Zhang Y,* Hong H, Hacker TA, Zegzebski JA, Theuer CP, Barnhart TE, Cai W. Positron emission tomography imaging of angiogenesis in a murine hindlimb ischemia model with 64Cu-labeled TRC105. Molecular Pharmaceutics, 2013, 10, 2749-2756. (PMID: PMC3836864)
110
Hong H,* Chen F,* Cai W. Pharmacokinetic issues of imaging with nanoparticles: focusing on carbon nanotubes and quantum dots. Molecular Imaging and Biology, 2013, 15, 507-520. (PMCID: PMC3773279)
109
Nayak TR, Krasteva LK, Cai W. Multimodality imaging of RNA interference. Current Medicinal Chemistry, 2013, 20, 3664-3675. (PMCID: PMC3749287)
108
Hernandez R, Orbay H, Cai W. Molecular imaging strategies for in vivo tracking of microRNAs: a comprehensive review. Current Medicinal Chemistry, 2013, 20, 3594-3603. (PMCID: PMC3749288)
107
Zhang Y, Hong H, Nayak TR, Valdovinos HF, Myklejord DV, Theuer CP, Barnhart TE, Cai W. Imaging tumor angiogenesis in breast cancer experimental lung metastasis with positron emission tomography, near-infrared fluorescence, and bioluminescence. Angiogenesis, 2013, 16, 663-674. ( PMCID: PMC3706271)
106
Hafeez BB, Zhong W, Fischer JW, Mustafa A, Shi X, Meske L, Hong H, Cai W, Havighurst T, Kim KM, Verma AK. Plumbagin, a medicinal plant (Plumbago zeylanica)-derived 1,4-naphthoquinone, inhibits growth and metastasis of human prostate cancer PC-3M-luciferase cells in an orthotopic xenograft mouse model. Molecular Oncology, 2013, 7, 428-439. (PMCID: PMC3625495)
105
Shi S, Yang K, Hong H, Valdovinos HF, Nayak TR, Zhang Y, Theuer CP, Barnhart TE, Liu Z, Cai W. Tumor vasculature targeting and imaging in living mice with reduced graphene oxide. Biomaterials, 2013, 34, 3002-3009. (PMCID: PMC3570619)
104
Hong H,* Zhang Y,* Orbay H, Nayak TR, Valdovinos HF, Bean J, Theuer CP, Barnhart TE, Cai W. Positron emission tomography imaging of tumor angiogenesis with a 61/64Cu-labeled F(ab’)2 antibody fragment. Molecular Pharmaceutics, 2013, 10, 709-716. (PMCID: PMC3563848)
103
Hong H, Benink HA, Uyeda HT, Valdovinos HF, Zhang Y, Meisenheimer P, Barnhart TE, Fan F, Cai W. HaloTag as a reporter gene: positron emission tomography imaging with 64Cu-labeled second generation HaloTag ligands. American Journal of Translational Research, 2013, 5, 291-302. (PMCID: PMC3633972)
102
Zhang Y,* Hong H,* Orbay H, Nayak TR, Valdovinos HF, Theuer CP, Barnhart TE, Cai W. PET imaging of CD105/endoglin expression with a 61/64Cu-labeled Fab antibody fragment. European Journal of Nuclear Medicine and Molecular Imaging, 2013, 40, 759-767. (PMCID: PMC3625465)
101
Orbay H, Hong H, Zhang Y, Cai W. PET/SPECT imaging of hindlimb ischemia: focusing on angiogenesis and blood flow. Angiogenesis, 2013, 16, 279-287. (PMCID: PMC3596452)

 

2012

100 Zhang Y,* Hong H,* Niu G, Valdovinos HF, Orbay H, Nayak TR, Chen X, Barnhart TE, Cai W. Positron emission tomography imaging of vascular endothelial growth factor receptor expression with 61Cu-labeled lysine-tagged VEGF121. Molecular Pharmaceutics, 2012, 9, 3586-3594. (PMCID: PMC3619014)
99 Zhang Y,* Hong H,* Severin GW, Engle JW, Yang Y, Goel S, Nathanson AJ, Liu G, Nickles RJ, Leigh BR, Barnhart TE, Cai W. ImmunoPET and near-infrared fluorescence imaging of CD105 expression using a monoclonal antibody dual-labeled with 89Zr and IRDye 800CW. American Journal of Translational Research, 2012, 4, 333-346. (PMCID: PMC3426387)
98 Xiao Y, Hong H, Matson VZ, Javadi A, Xu W, Yang Y, Zhang Y, Engle JW, Nickles RJ, Cai W, Steeber DA, Gong S. Gold nanorods conjugated with doxorubicin and cRGD for combined anticancer drug delivery and PET imaging. Theranostics, 2012, 2, 757-768. (PMCID: PMC3425121)
97 Hong H,* Zhang Y,* Severin GW, Yang Y, Engle JW, Niu G, Nickles RJ, Chen X, Leigh BR, Barnhart TE, Cai W. Multimodality imaging of breast cancer experimental lung metastasis with bioluminescence and a monoclonal antibody dual-labeled with 89Zr and IRDye 800CW. Molecular Pharmaceutics, 2012, 9, 2339-2349. (PMCID: PMC3500677)
96 Zhang Y,* Nayak TR,* Hong H, Cai W. Graphene: a versatile nanoplatform for biomedical applications. Nanoscale, 2012, 4, 3833-3842. (PMCID: PMC3376191)
95 Hong H, Zhang Y, Nayak TR, Engle JW, Wong HC, Liu B, Barnhart TE, Cai W. ImmunoPET of tissue factor in pancreatic cancer. Journal of Nuclear Medicine, 2012, 53, 1748-1754. (PMCID: PMC3489969)
94 Engle JW,* Hong H,* Zhang Y, Valdovinos HF, Myklejord DV, Barnhart TE, Theuer CP, Nickles, RJ, Cai W. Positron emission tomography imaging of tumor angiogenesis with a 66Ga-labeled monoclonal antibody. Molecular Pharmaceutics, 2012, 9, 1441-1448. (PMCID: PMC3375902)
93 Yang Y,* Niu Y,* Hong H, Wu H, Zhang Y, Engle JW, Barnhart TE, Cai J, Cai W. Radiolabeled γ-AApeptides: a new class of tracers for positron emission tomography. Chemical Communications, 2012, 48, 7850-7852. (PMCID: PMC3397393)
92 Zhang Y, Cai W. Molecular imaging of insulin-like growth factor 1 receptor in cancer. American Journal of Nuclear Medicine and Molecular Imaging, 2012, 2, 248-259. (PMCID: PMC3477732)
91 Cai W, Hong H. In a “nutshell”: intrinsically radio-labeled quantum dots. American Journal of Nuclear Medicine and Molecular Imaging, 2012, 2, 136-140. (PMCID: PMC3477731)
90 Hong H,* Zhang Y,* Engle JW, Nayak TR, Theuer CP, Nickles RJ, Barnhart TE, Cai W. In vivo targeting and positron emission tomography imaging of tumor vasculature with 66Ga-labeled nano-graphene. Biomaterials, 2012, 33, 4147-4156. (PMCID: PMC3313015)
89 Zhang Y,* Hong H,* Engle JW, Yang Y, Theuer CP, Barnhart TE, Cai W. Positron emission tomography and optical imaging of tumor CD105 expression with a dual-labeled monoclonal antibody. Molecular Pharmaceutics, 2012, 9, 645-653. (PMCID: PMC3295892)
88 Hong H,* Yang K,* Zhang Y, Engle JW, Feng L, Yang Y, Nayak TR, Goel S, Bean J, Theuer CP, Barnhart TE, Liu Z, Cai W. In vivo targeting and imaging of tumor vasculature with radiolabeled, antibody-conjugated nano-graphene. ACS Nano, 2012, 6, 2361-2370. (PMCID: PMC3314116) (Highlighted in Chemical & Engineering News)
87 Xiao Y,* Hong H,* Javadi A, Engle JW, Xu W, Yang Y, Zhang Y, Barnhart TE, Cai W, Gong S. Multifunctional unimolecular micelles for cancer-targeted drug delivery and positron emission tomography imaging. Biomaterials, 2012, 33, 3071-3082. (PMCID: PMC3313838)
86 Zhang Y, Hong H, Engle JW, Yang Y, Barnhart TE, Cai W. Positron emission tomography and near-infrared fluorescence imaging of vascular endothelial growth factor with dual-labeled bevacizumab. American Journal of Nuclear Medicine and Molecular Imaging, 2012, 1, 1-13. (PMCID: PMC3249831)
85 Hong H, Severin GW, Yang Y, Engle JW, Zhang Y, Barnhart TE, Liu G, Leigh BR, Nickles RJ, Cai W. Positron emission tomography imaging of CD105 expression with 89Zr-Df-TRC105. European Journal of Nuclear Medicine and Molecular Imaging, 2012, 39, 138-148. (PMCID: PMC3228902)

 

2011

84
Zhang Y, Hong H, Engle JW, Bean J, Yang Y, Leigh BR, Barnhart TE, Cai W. Positron emission tomography imaging of CD105 expression with a 64Cu-labeled antibody: NOTA is superior to DOTA. PLoS ONE, 2011, 6, e28005. (PMCID: PMC3235104)
83
Hong H, Shi J, Yang Y, Zhang Y, Engle JE, Nickles NJ, Wang X, Cai W. Cancer-targeted optical imaging with fluorescent zinc oxide nanowires. Nano Letters, 2011, 11, 3744-3750. (PMCID: PMC3173586)
82
Zhang Y, Hong H, Myklejord DV, Cai W. Molecular imaging with SERS-active nanoparticles. Small, 2011, 7, 3261-3269. (PMCID: PMC3228876)
81
Hong H, Benink HA, Zhang Y, Yang Y, Uyeda HT, Engle JW, Severin GW, McDougall MG, Barnhart TE, Klaubert DH, Nickles RJ, Fan F, Cai W. HaloTag: A novel reporter gene for positron emission tomography. American Journal of Translational Research, 2011, 3, 392-403. (PMCID: PMC3158741)
80
Cai W, Hong H. Peptoid and positron emission tomography: an appealing combination. American Journal of Nuclear Medicine and Molecular Imaging, 2011, 1, 76-79. (PMCID: PMC3183479)
79
Cai W, Zhang Y, Kamp TJ. Imaging of induced pluripotent stem cells: from cellular reprogramming to transplantation. American Journal of Nuclear Medicine and Molecular Imaging, 2011, 1,18-28. (PMCID: PMC3155258)
78
Zhang Y, Hong H, Cai W. Tumor-targeted drug delivery with aptamers. Current Medicinal Chemistry, 2011, 18, 4185-4194. (PMCID: PMC3205327)
77
Yang Y,* Zhang Y,* Hong H, Liu G, Leigh BR, Cai W. In vivo near-infrared fluorescence imaging of CD105 expression during tumor angiogenesis. European Journal of Nuclear Medicine and Molecular Imaging, 2011, 38, 2066-2076. (PMCID: PMC3189267)
76
Hong H, Goel S, Zhang Y, Cai W. Molecular imaging with nucleic acid aptamers. Current Medicinal Chemistry, 2011, 18, 4195-4205. (PMCID: PMC3205285)
75
Shi J, Hong H, Ding Y, Yang Y, Wang F, Cai W, Wang X. Evolution of zinc oxide nanostructures through kinetics control. Journal of Materials Chemistry 2011,21, 9000-9008. (Inside Cover) (PMCID: PMC3130520)
74
Wang P, Yang Y, Hong H, Zhang Y, Cai W, D Fang. Aptamers as therapeutics in cardiovascular diseases. Current Medicinal Chemistry, 2011, 18, 4169-4174. (PMCID: PMC3205281)
73
Yang X, Hong H, Grailer JJ, Rowland IJ, Javadi A, Hurley SA, Xiao Y, Yang Y, Zhang Y, Nickles RJ, Cai W, Steeber DA, Gong S. cRGD-functionalized, DOX-conjugated, and 64Cu-labeled superparamagnetic iron oxide nanoparticles for targeted anticancer drug delivery and PET/MR imaging. Biomaterials, 2011,32, 4151-4160. (PMCID: PMC3292876)
72
Wang RE, Zhang Y, Cai J, Cai W, Gao T. Aptamer-based fluorescent biosensors. Current Medicinal Chemistry, 2011, 18, 4175-4184. (PMCID: PMC3205236)
71
Zhang Y, Hong H, Cai W. PET tracers based on Zr-89.Current Radiopharmaceuticals, 2011, 4, 131-139. (PMCID: PMC3205236)
70
Hong H,* Yang Y,* Zhang Y,* Engle JW, Barnhart TE, Nickles RJ, Leigh BR, Cai W. Positron emission tomography imaging of CD105 expression during tumor angiogenesis. European Journal of Nuclear Medicine and Molecular Imaging, 2011, 38, 1335-1343.(PMCID: PMC3105181)
69
Zhang Y, Yang Y, Cai W. Multimodality imaging of integrin αvβ3 expression. Theranostics, 2011, 1, 135-148. (PMCID: PMC3086621)
68
Zhang Y, Yang Y, Hong H, Cai W. Multimodality molecular imaging of CD105 (endoglin) expression. International Journal of Clinical and Experimental Medicine, 2011, 4, 32-42. (PMCID: PMC3048982)

 

2010

67
Hong H, Yang Y, Zhang Y, Cai W. Non-invasive cell tracking in cancer and cancer therapy. Current Topics in Medicinal Chemistry, 2010, 10, 1237-1248. (PMCID: PMC2916057)
66
Zhang Y, Hong H, Cai W. Imaging with Raman spectroscopy. Current Pharmaceutical Biotechnology, 2010, 11, 654-661. (PMCID: PMC2917525)
65 Hong H, Yang Y, Zhang Y, Cai W. Non-invasive imaging of human embryonic stem cells. Current Pharmaceutical Biotechnology, 2010, 11, 685-692. (PMCID: PMC2917512)
64 Hong H, Yang Y, Liu B, Cai W. Imaging of abdominal aortic aneurysm: the present and the future. Current Vascular Pharmacology, 2010, 8, 808-819. (PMCID: PMC2891873)
63 Hong H, Zhang Y, Cai W. In vivo imaging of RNA interference. Journal of Nuclear Medicine, 2010, 51, 169-172. (PMCID: PMC2832477)
62 Hong H, Zhang Y, Sun J, Cai W. Positron emission tomography imaging of prostate cancer. Amino Acids, 2010, 39, 11-27. (PMCID: PMC2883014)

 

2009

61 Hong H, Zhang Y, Sun J, Cai W. Molecular imaging and therapy of cancer with radiolabeled nanoparticles. Nano Today, 2009, 4, 399-413. (PMCID: PMC2753977)
60 Yang Y, Hong H, Zhang Y, Cai W. Molecular imaging of proteases in cancer. Cancer Growth and Metastasis, 2009, 2, 13-27. (PMCID: PMC2838618)
59 Hong H, Sun J, Cai W. Multimodality imaging of nitric oxide and nitric oxide synthases. Free Radical Biology & Medicine, 2009, 47, 684-698.(PMID: 19524664)
58 Hong H, Gao T, Cai W. Molecular imaging with single-walled carbon nanotubes. Nano Today, 2009, 4, 252-261. (PMCID: PMC3132891)

 

2008

57
Hong H, Sun J, Cai W. Radionuclide-based cancer imaging targeting the carcinoembryonic antigen. Biomarker Insights, 2008, 3, 435-451. (PMCID: PMC2688357)
56
Hong H, Sun J, Cai W. Anatomical and molecular imaging of skin cancer. Clinical, Cosmetic and Investigational Dermatology, 2008, 1, 1-17. (PMCID: PMC3048596)
55 Cai W, Kerner ZJ, Hong H, Sun J. Targeted cancer therapy with tumor necrosis factor-alpha. Biochemistry Insights, 2008, 1, 5-21.
54 Cai W, Gao T, Hong H, Sun J. Applications of gold nanoparticles in cancer nanotechnology. Nanotechnology, Science and Applications, 2008, 1, 17-32.
53 Cai W, Niu G, Chen X. Imaging of integrins as biomarkers for tumor angiogenesis. Current Pharmaceutical Design, 2008, 14, 2943-2973. (PMID: 18991712)
52 Cai W, Gambhir SS, Chen X. Molecular imaging of tumor vasculature. Methods in Enzymology, 2008, 445, 141-176.(PMID: 19022059)
51 Cai W, Chen X. Multimodality molecular imaging of tumor angiogenesis. Journal of Nuclear Medicine, 2008, 49, 113S-128S. (PMID: 18523069)

 

Before UW-Madison

50
Cao F, Li Z, Lee A, Liu Z, Chen K, Wang H, Cai W, Chen X, Wu JC. Noninvasive de novo imaging of human embryonic stem cell-derived teratoma formation. Cancer Research, 2009, 69, 2709-2713.
49
Cai W,* Guzman R,* Hsu AR, Wang H, Chen K, Sun G, Gera A, Choi R, Bliss T, He L, Li ZB, Maag ALD, Hori N, Zhao H, Moseley M, Steinberg GK, Chen X. Positron emission tomography imaging of post-stroke angiogenesis. Stroke, 2009, 40, 270-277.
48 Chen K,* Cai W,* Li ZB, Wang H, Chen X. Quantitative PET imaging of VEGF receptor expression. Molecular Imaging and Biology, 2009, 11, 15-22.
47 Veeravagu A, Liu Z, Niu G, Chen K, Jia B, Cai W, Jin C, Hsu AR, Connolly AJ, Tse V, Wang F, Chen X. Integrin αvβ3-targeted radioimmunotherapy of glioblastoma multiforme. Clinical Cancer Research, 2008, 14, 7330-7339.
46 Chen K, Li ZB, Wang H, Cai W, Chen X. Dual modality optical and positron emission tomography imaging of vascular endothelial growth factor receptor on tumor vasculature using quantum dots. European Journal of Nuclear Medicine and Molecular Imaging, 2008, 35, 2235-2244.
45 Cai W, Niu G, Chen X. Multimodality imaging of the HER-kinase axis in cancer. European Journal of Nuclear Medicine and Molecular Imaging, 2008, 35, 186-208.
44 Cao Q, Cai W, Niu G, He L, Chen X. Multimodality imaging of IL-18-binding protein-Fc therapy of experimental lung metastasis. Clinical Cancer Research, 2008, 14, 6137-6145.
43 Liu Z, Davis C, Cai W, He L, Chen X, Dai H. Circulation and long-term fate of functionalized, biocompatible single-walled carbon nanotubes in mice probed by Raman spectroscopy. Proceedings of the National Academy of Sciences of the United States of America, 2008, 105, 1410-1415. (PMCID: PMC2234157)
42 Wang H, Chen K, Cai W, Li ZB, He L, Kashefi A, Chen X. Integrin-targeted imaging and therapy with RGD4C-TNF fusion protein. Molecular Cancer Therapeutics, 2008, 7, 1044-1053. 
41 Veeravagu A, Hou LC, Hsu AR, Cai W, Greve JM, Chen X, Tse V. The temporal correlation of dynamic contrast-enhanced magnetic resonance imaging with tumor angiogenesis in a murine glioblastoma model. Neurological Research, 2008, 30, 952-959.
40 Willmann JK, Chen K, Wang H, Paulmurugan R, Rollins M, Cai W, Wang DS, Chen IY, Gheysens O, Rodriguez-Porcel M, Chen X, Gambhir SS. Monitoring of the biological response to murine hindlimb ischemia with 64Cu-labeled vascular endothelial growth factor-121 positron emission tomography. Circulation, 2008, 117, 915-922. 
39 Cai W, Chen X. Preparation of peptide-conjugated quantum dots for tumor vasculature-targeted imaging. Nature Protocols, 2008, 3, 89-96.
38 Niu G, Cai W, Chen K, Chen X. Non-invasive PET imaging of EGFR degradation induced by a heat shock protein 90 inhibitor. Molecular Imaging and Biology, 2008, 10, 99-106.
37 Niu G, Cai W, Chen X. Molecular imaging of human epidermal growth factor receptor 2 (HER-2) expression. Frontiers in Bioscience, 2008, 13, 790-805.
36 Rodriguez-Porcel M, Cai W, Gheysens O, Willman JK, Chen K, Wang H, Chen IY, He L, Wu JC, Li ZB, Mohamedali KA, Kim S, Rosenblum MG, Chen X, Gambhir SS. Imaging of VEGF receptor in a rat myocardial infarction model using PET. Journal of Nuclear Medicine, 2008, 49, 667-673.
35 Cai W, Olafsen T, Zhang X, Cao Q, Gambhir SS, Williams LE, Wu AM, Chen X. PET imaging of colorectal cancer in xenograft-bearing mice by use of an 18F-labeled T84.66 anti-carcinoembryonic antigen diabody. Journal of Nuclear Medicine, 2007, 48, 304-310.
34 Cai W, Chen X. Nanoplatforms for targeted molecular imaging in living subjects. Small, 2007, 3, 1840-1854.
33 Wu Z, Li ZB, Chen K, Cai W, He L, Chin FT, Li F, Chen X. MicroPET of tumor integrin αvβ3 expression using 18F-labeled PEGylated tetrameric RGD peptide (18F-FPRGD4). Journal of Nuclear Medicine, 2007, 48, 1536-1544.
32 Cai W, Chen K, Li ZB, Gambhir SS, Chen X. Dual-function probe for PET and near-infrared fluorescence imaging of tumor vasculature. Journal of Nuclear Medicine, 2007, 48, 1862-1870.
31 Wang H,* Cai W,* Chen K, Li ZB, Kashefi A, He L, Chen X. A new PET tracer specific for vascular endothelial growth factor receptor 2. European Journal of Nuclear Medicine and Molecular Imaging, 2007, 34, 2001-2010. 
30 Cai W,* Ebrahimnejad A,* Chen K, Cao Q, Li ZB, Tice DA, Chen X. Quantitative radioimmunoPET imaging of EphA2 in tumor-bearing mice. European Journal of Nuclear Medicine and Molecular Imaging, 2007, 34, 2024-2036.
29 Cai W, Hsu AR, Li ZB, Chen X. Are quantum dots ready for in vivo imaging in human subjects? Nanoscale Research Letters, 2007, 2, 265-281. 
28 Cai W, Chen X. Multimodality imaging of vascular endothelial growth factor and vascular endothelial growth factor receptor expression. Frontiers in Bioscience, 2007, 12, 4267-4279.
27 Cao Q,* Cai W,* Li ZB, Chen K, He L, Li HC, Hui M, Chen X. PET imaging of acute and chronic inflammation in living mice. European Journal of Nuclear Medicine and Molecular Imaging, 2007, 34, 1832-1842.
26 Li ZB, Cai W, Cao Q, Chen K, Wu Z, He L, Chen X. 64Cu-labeled tetrameric and octameric RGD peptides for small-animal PET of tumor αvβ3 integrin expression. Journal of Nuclear Medicine, 2007, 48, 1162-1171.
25 Wu Z, Li ZB, Cai W, He L, Chin FT, Li F, Chen X. 18F-labeled mini-PEG spacered RGD dimer (183:07 PM 1/3/2012F-FPRGD2): synthesis and microPET imaging of αvβ3 integrin expression. European Journal of Nuclear Medicine and Molecular Imaging, 2007, 34, 1823-1831.
24 Veeravagu A, Hsu AR, Cai W, Hou LC, Tse VCK, Chen X. Vascular endothelial growth factor and vascular endothelial growth factor receptor inhibitors as anti-angiogenic agents in cancer therapy. Recent Patents on Anti-Cancer Drug Discovery, 2007, 2, 59-71.
23 Li ZB, Cai W, Chen X. Semiconductor quantum dots for in vivo imaging. Journal of Nanoscience and Nanotechnology, 2007, 7, 2567-2581.
22 Niu G, Xiong Z, Cheng Z, Cai W, Gambhir SS, Xing L, Chen X. In vivo bioluminescence tumor imaging of RGD peptide-modified adenoviral vector encoding firefly luciferase reporter gene. Molecular Imaging and Biology, 2007, 9, 126-134.
21 Cai W,* Chen K,* He L, Cao Q, Koong A, Chen X. Quantitative PET of EGFR expression in xenograft-bearing mice using 64Cu-labeled cetuximab, a chimeric anti-EGFR monoclonal antibody. European Journal of Nuclear Medicine and Molecular Imaging, 2007, 34, 850-858.
20 Hsu AR,* Cai W,* Veeravagu A, Mohamedali KA, Chen K, Vogel H, Hou LC, Tse VCK, Rosenblum MG, Chen X. Multimodality molecular imaging of glioblastoma growth inhibition with vasculature-targeting fusion toxin VEGF121/rGel. Journal of Nuclear Medicine, 2007, 48, 445-454.
19 Liu Z,* Cai W,* He L, Nakayama N, Chen K, Sun X, Chen X, Dai H. In-vivo biodistribution and highly efficient tumor targeting of carbon nanotubes in mice. Nature Nanotechnology, 2007, 2, 47-52. (Cited > 270 times)
18 Hsu AR, Veeravagu A, Cai W, Hou LC, Tse V, Chen X. Integrin αvβ3 antagonists for anti-angiogenic cancer treatment. Recent Patents on Anti-Cancer Drug Discovery, 2007, 2, 143-158.
17 Zhang X, Cai W, Cao F, Schreibmann E, Wu Y, Wu JC, Xing L, Chen X. 18F-labeled bombesin analogs for targeting GRP receptor-expressing prostate cancer. Journal of Nuclear Medicine, 2006, 47, 492-501.
16 Zhang X, Xiong Z, Wu Y, Cai W, Tseng JR, Gambhir SS, Chen X. Quantitative PET imaging of tumor integrin αvβ3 expression with 18F-FRGD2. Journal of Nuclear Medicine, 2006, 47, 113-121. 
15 Cao Q, Cai W, Li T, Yang Y, Chen K, Xing L, Chen X. Combination of integrin siRNA and irradiation for breast cancer therapy. Biochemical and Biophysical Research Communications, 2006, 351, 726-732.
14 Cai W,* Chen K,* Mohamedali KA, Cao Q, Gambhir SS, Rosenblum MG, Chen X. PET of vascular endothelial growth factor receptor expression. Journal of Nuclear Medicine, 2006, 47, 2048-2056.
13 Cai W, Rao J, Gambhir SS, Chen X. How molecular imaging is speeding up anti-angiogenic drug development. Molecular Cancer Therapeutics, 2006, 5, 2624-2633.
12 Cai W, Wu Y, Chen K, Cao Q, Tice DA, Chen X. In vitro and in vivo characterization of 64Cu-labeled AbegrinTM, a humanized monoclonal antibody against integrin αvβ3. Cancer Research, 2006, 66, 9673-9681.
11 Wu Y, Cai W, Chen X. Near-infrared fluorescence imaging of tumor integrin αvβ3 expression with Cy7-labeled RGD multimers. Molecular Imaging and Biology, 2006, 8, 226-236. (PMCID: PMC1643841)
10 Cai W, Shin DW, Chen K, Gheysens O, Cao Q, Wang SX, Gambhir SS, Chen X. Peptide-labeled near-infrared quantum dots for imaging tumor vasculature in living subjects. Nano Letters, 2006, 6, 669-676. (Cited > 300 times)
9 Cai W,* Zhang X,* Wu Y, Chen X. A thiol-reactive 18F-labeling agent, N-[2-(4-18F-fluorobenzamido)ethyl]maleimide (18F-FBEM), and the synthesis of RGD peptide-based tracer for PET imaging of αvβ3 integrin expression. Journal of Nuclear Medicine, 2006, 47, 1172-1180. (PMCID: PMC1704081)
8 Cai W, Chen X. Anti-angiogenic cancer therapy based on integrin αvβ3 antagonism. Anti-cancer Agents in Medicinal Chemistry, 2006, 6, 407-428.
7 Cai W, Gambhir SS, Chen X. Multimodality tumor imaging targeting integrin αvβ3. BioTechniques, 2005, 39, S6-S17. 
6 Cai W, Taulane JP, Sorto NA, Oganesyan A,Gutierrez CG, Goodman M. Scaffold assembly of collagen-like triple helices at the C-terminus. Letters in Organic Chemistry, 2007, 4, 96-101.
5 Cai W, Wong D, Kinberger GA, Kwok SW, Taulane JP, Goodman M. Facile and efficient assembly of collagen-like triple helices on a TRIS scaffold. Bioorganic Chemistry, 2007, 35, 327-337.
4 Cai W, Kwok SW, Taulane JP, Goodman M. Metal-assisted assembly and stabilization of collagen-like triple helices. Journal of the American Chemical Society, 2004, 126, 15030-15031. 
3 Goodman M, Cai W, Kinberger GA. The new science of protein mimetics. Macromolecular Symposia, 2003, 201, 223-236.
2 Goodman M, Cai W, Smith ND. The bold legacy of Emil Fisher. Journal of Peptide Science, 2003, 9, 594-603. 
1 Kinberger GA, Cai W, Goodman M. Collagen mimetic dendrimers. Journal of the American Chemical Society, 2002, 124, 15162-15163. 

 

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